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Record Nr. |
UNINA9910828363003321 |
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Autore |
Southwood Robin L. |
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Titolo |
Concepts in clinical pharmacokietics / / Robin Southwood, Virginia H. Fleming, Gary Huckaby |
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Pubbl/distr/stampa |
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Bethesda, MD : , : ASHP publication, , [2018] |
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2018 |
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ISBN |
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Edizione |
[Seventh edition.] |
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Descrizione fisica |
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1 online resource (x, 284 pages) |
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Disciplina |
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Soggetti |
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Drugs - Dosage |
Pharmacokinetics |
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Lingua di pubblicazione |
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Formato |
Materiale a stampa |
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Livello bibliografico |
Monografia |
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Nota di contenuto |
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Introduction to pharmacokinetics and pharmacodynamics -- Basic pharmacokinetics -- Half-life, elimination rate, and AUC -- Intravenous bolus administration, multiple drug administration, and steady-state average concentrations -- Relationships of pharmacokinetic parameters and intravenous intermittent and continuous infusions -- Two-compartment models -- Biopharmaceutics : absorption -- Drug distribution and protein binding -- Drug elimination processes -- Nonlinear processes -- Pharmacokinetic variation and model-independent relationships -- Aminoglycosides -- Vancomycin -- Theophylline -- Phenytoin and digoxin. |
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Sommario/riassunto |
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Understanding the science of pharmacokinetics is a challenge for many pharmacy students and practitioners. Concepts in Clinical Pharmacokinetics, now in its 7th edition, has helped thousands by simplifying this essential, but complex, subject to reflect current practice. The 7th edition has been revised by Robin Southwood, PharmD, BC-ADM, CDE; Virginia H. Fleming, PharmD, BCPS; and Gary Huckaby, PharmD; all experts in clinical pharmacy education. Together, they have updated and expanded the text to include the latest information and insights on concepts through extensive use of correlates, figures, and review questions. Inside you will find: * 15 easy-to-follow lessons, perfect for a semester * Practice quizzes to help chart progress * Enhanced discussion of hemodialysis * A |
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phenytoin "cheat sheet" to help you through the calculations maze * New vancomycin cases based on higher desired vancomycin levels and trough-only dose estimations * Expanded information on modified diet in renal disease formula versus Cockcroft-Gault formula methods * Factors to consider when choosing a dosing/body weight for various equations * Updated clinical correlates, discussion points, references, and questions/answers Concepts in Clinical Pharmacokinetics is the fundamental reference for learning the basic, foundational pharmacokinetics concepts and how to apply them in clinical practice. |
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