1.

Record Nr.

UNINA990006584170403321

Autore

Pocock, J. G. A. <John Greville Agard ; <1924-

Titolo

Il momento machiavelliano / John Pocock

Pubbl/distr/stampa

Bologna : il Mulino, 1980

Descrizione fisica

2 v. ; 21 cm

Collana

Storiografia

Disciplina

321.86

Locazione

FSPBC

DFD

DDCIC

BFS

Collocazione

XII A 587 (I)

XII A 587 (II)

XI C P 40(1)

XI C P 40(2)

III 93:1

III 93:2

321.86 POC 1,1

321.86 POC 1,2

Lingua di pubblicazione

Italiano

Formato

Materiale a stampa

Livello bibliografico

Monografia

Nota di contenuto

1.: Il pensiero politico fiorentino 2.: La repubblica nel pensiero politico anglosassone



2.

Record Nr.

UNINA9910830413303321

Titolo

Practical methods for biocatalysis and biotransformations . 3 / / edited by John Whittall, Manchester Interdisciplinary Biocentre (MIB), The University of Manchester, UK, Peter W. Sutton, GlaxoSmithKline Research and Development Limited, UK, Wolfgang Kroutil, Department of Chemistry, Organic and Bioorganic Chemistry, University of Graz, Austria

Pubbl/distr/stampa

Chichester, West Sussex : , : John Wiley & Sons, Limited, , 2016

ISBN

1-5231-1471-1

1-118-69629-8

1-118-69628-X

Edizione

[3.]

Descrizione fisica

1 online resource (319 p.)

Disciplina

660.6/34

Soggetti

Enzymes - Biotechnology

Biocatalysis

Biotransformation (Metabolism)

Organic compounds - Synthesis

Lingua di pubblicazione

Inglese

Formato

Materiale a stampa

Livello bibliografico

Monografia

Note generali

Description based upon print version of record.

Nota di bibliografia

Includes bibliographical references and index.

Nota di contenuto

Practical Methods for Biocatalysis and Biotransformations 3; Contents; List of Contributors; Abbreviations; Chapter 1: Considerations for the Application of Process Technologies in Laboratory- and Pilot-Scale Biocatalysis for Chemical Synthesis; 1.1 Introduction; 1.2 Process Intensification and Proposed Scale-Up Concept; 1.3 Enabling Technologies; 1.3.1 Biocatalyst Immobilization; 1.3.1.1 General Considerations for Implementation; 1.3.1.2 Carrier-Bound Supported Enzymes; 1.3.1.2.1 Adsorption; Considerations for Implementation; 1.3.1.2.2 Covalent Binding; Considerations for Implementation

1.3.1.2.3 Ionic BindingConsiderations for Implementation; 1.3.1.3 Carrier-Free Immobilization; 1.3.1.3.1 Cross-Linked Enzyme Aggregates (CLEAsTM); Considerations for Implementation; 1.3.2 Reactor Options; 1.3.2.1 Ideal Reactors; 1.3.2.2 Modes of Operation; 1.3.2.3 Well-Mixed Reactor Hydrodynamics; 1.3.2.3.1 Stirred Tanks;



Considerations for Implementation; 1.3.2.3.2 Batch Stirred-Tank Reactors (BSTRs); Considerations for Implementation; 1.3.2.3.3 Continuous Stirred-Tank Reactors (CSTRs); Considerations for Implementation; 1.3.2.3.4 Alternative Well-Mixed Reactors

Continuous Fluidized-Bed Reactors (CFBRs)Considerations for Implementation; Continuous Packed-Bed Reactors (CPBRs); Considerations for Implementation; Continuous Expanded-Bed Reactors (CEBRs); Considerations for Implementation; 1.3.2.3.5 Membrane Bioreactors (MBRs); Considerations for Implementation; 1.4 Enhancing Technologies; 1.4.1 In Situ Product Removal (ISPR); 1.4.1.1 Considerations for Implementation; 1.4.1.2 ISPR by Adsorption on Resins; 1.4.1.2.1 Considerations for Implementation; 1.4.1.3 ISPR Using Expanded-Bed Adsorption (EBA); 1.4.1.3.1 Considerations for Implementation

1.4.1.4 ISPR by Crystallization1.4.1.4.1 Considerations for Implementation; 1.4.2 Substrate Feeding Strategies; 1.4.2.1 Fed-Batch Operation; 1.4.2.1.1 Considerations for Implementation; 1.4.3 Non-Conventional Media; 1.4.3.1 Single Non-Conventional Liquid Phase Systems; 1.4.3.1.1 Considerations for Implementation; 1.4.3.2 Aqueous-Organic Two-Liquid Phase Systems; 1.4.3.2.1 Considerations for Implementation; 1.4.3.3 Aqueous-Ionic Liquid Two-Liquid Phase Systems; 1.4.3.3.1 Considerations for Implementation; 1.4.4 Oxygen Supply Strategies; 1.4.4.1 Surface Aeration

1.4.4.1.1 Considerations for Implementation1.4.4.2 Sparged Aeration; 1.4.4.2.1 Considerations for Implementation; 1.4.4.3 Bubble-Column Reactors; 1.4.4.3.1 Considerations for Implementation; 1.5 Conclusion; References; Chapter 2: Cytochrome P450 (CYP) Progress in Biocatalysis for Synthetic Organic Chemistry; 2.1 Introduction; 2.2 CYP Development; 2.3 Recent Developments; 2.4 Conclusion; References; Chapter 3: Use of Hydrolases and Related Enzymes for Synthesis; 3.1 Continuous-Flow Reactor-Based Enzymatic Synthesis of Phosphorylated Compounds on a Large Scale; 3.1.1 Materials and Equipment

3.1.2 Immobilization of Acid Phosphatase on Immobeads



3.

Record Nr.

UNINA9910827884603321

Titolo

Mechanisms of alcohol damage in utero / / editors, Ruth Porter, Maeve O'Connor, Julie Whelan

Pubbl/distr/stampa

London, : Pitman

Newark, N.J., : Distributed in North America by CIBA Pharmaceutical Co., Medical Education Division, 1984

ISBN

9786613694515

9781280784125

1280784121

9780470720868

0470720867

9780470718568

0470718560

Edizione

[1st ed.]

Descrizione fisica

1 online resource (306 pages) : illustrations

Collana

Ciba Foundation symposium ; ; 105

Altri autori (Persone)

PorterRuth

O'ConnorMaeve

WhelanJulie

Disciplina

618.3/268

Soggetti

Fetal alcohol spectrum disorders

Fetus - Effect of drugs on

Alcoholism in pregnancy

Pathology, Experimental

Lingua di pubblicazione

Inglese

Formato

Materiale a stampa

Livello bibliografico

Monografia

Note generali

"Editors, Ruth Porter (organizer), Maeve O'Connor, and Julie Whelan"--P. v.

Nota di bibliografia

Includes bibliographical references and indexes.

Nota di contenuto

Mechanisms of alcohol damage in utero; Contents; Chairman's introduction: what do we know of the mechanisms of alcohol damage in utero?; Prenatal and early postnatal exposure to ethanol permanently alters the rat hippocampus; Discussion; Effects of alcohol on functional development of the auditory pathway in the brainstem of infants and chick embryos; Discussion; Altered stress responsiveness in adult rats exposed to ethanol in utero: neuroendocrine mechanisms; Discussion; General discussion I; Neuronal migration; Fetal breathing



Interaction of ethanol with neural cells in culture: a model of intoxication, tolerance and withdrawal Discussion; Growth, enzymes and hormonal changes in offspring of alcohol-fed rats; Discussion; Interactions between trace elements and alcohol in rats; Discussion; Critical periods for alcohol teratogenesis in mice, with special reference to the gastrulation stage of embryogenesis; Discussion; Range of alcohol-induced damage in the developing central nervous system; Discussion; Measures of alcohol damage in utero in the pigtailed macaque (Macaca nemestrina); Discussion

General discussion 2 Are results from different animal models consistent'? Alcohol exposure in utero and functional deficits in children during the first four years of life; Discussion; Clinical, psychopathological and developmental aspects in children with the fetal alcohol syndrome: a four-year follow-up study; Discussion; Growth of rat embryos in the serum of alcohol drinkers; Discussion; General discussion 3 What do we want from animal models?; Effects of moderate alcohol consumption and smoking on fetal outcome; Discussion

Preventing fetal alcohol effects: effectiveness of a demonstration project Discussion; Final general discussion; Prenatal diagnosis and counselling; Ethanol and teratogenic mechanisms; The importance of understanding the mechanism of alcohol damage to the brain in utero; Index of contributors; Subject index

Sommario/riassunto

The Novartis Foundation Series is a popular collection of the proceedings from Novartis Foundation Symposia, in which groups of leading scientists from a range of topics across biology, chemistry and medicine assembled to present papers and discuss results. The Novartis Foundation, originally known as the Ciba Foundation, is well known to scientists and clinicians around the world.