1.

Record Nr.

UNINA9910827881903321

Titolo

Biochemistry and pharmacology of platelets

Pubbl/distr/stampa

Amsterdam ; ; New York, : Elsevier, 1975

Amsterdam ; ; New York : , : Elsevier, , 1975

ISBN

9786613693891

9781280783500

1280783508

9780470720172

0470720174

9780470717851

0470717858

Edizione

[1st ed.]

Descrizione fisica

1 online resource (362 pages) : illustrations, charts

Collana

Ciba Foundation Symposium (new series) ; ; 35

Disciplina

612.39

Soggetti

Blood platelets

Lingua di pubblicazione

Inglese

Formato

Materiale a stampa

Livello bibliografico

Monografia

Note generali

"Symposium on Biochemistry and Pharmacology of Platelets, held at the Ciba Foundation, London, 21st-23rd January, 1975"--Participants page.

Nota di bibliografia

Includes bibliographical references and indexes.

Nota di contenuto

Biochemistry and Pharmacology of Platelets; Contents; Introduction: some current problems; Common pathways of membrane reactivity after stimulation of platelets by different agents; Discussion; Binding of adenosine diphosphate by human platelet membrane; Discussion; Enzyme activities on the platelet surface in relation to the action of adenosine diphosphate; Discussion; Stimulus-response coupling in the thrombin-platelet interaction; Discussion; The interaction of platelet actin, myosin and myosin light chain kinase; Discussion; Roles of cyclic nucleotides in platelet function; Discussion

Initial biochemical responses of platelets to stimulation Discussion; Biochemistry of the platelet release reaction; Discussion; Prostaglandins and precursors in platelet function; Discussion; Significance of glucose and glycogen meta-bolism for platelet function; Discussion; Elemental composition of platelet dense bodies; Discussion; The organelles storing 5-hydroxytryptamine in blood platelets; Discussion; 5-



Hydroxytryptamine receptors of platelets; Discussion; Interactions between 5-hydroxytryptamine and platelet lipid fractions; Discussion; General Discussion

Nomenclature of the release reaction Activation of platelets; Oxidative phosphorylation; Primary aggregation by 5HT, vasopressin and thrombin; Index of contributors; Subject index

Sommario/riassunto

The Novartis Foundation Series is a popular collection of the proceedings from Novartis Foundation Symposia, in which groups of leading scientists from a range of topics across biology, chemistry and medicine assembled to present papers and discuss results. The Novartis Foundation, originally known as the Ciba Foundation, is well known to scientists and clinicians around the world.