Mobility and function in proteins and nucleic acids

• Record Nr.: UNINA9910827879303321
• Pubbl/distr/stampa: London, : Pitman, 1983
• ISBN: 9786613694447; 9781280784057; 1280784059; 9780470720752; 0470720751; 9780470718445; 0470718447
• Edizione: [1st ed.]
• Descrizione fisica: 1 online resource (369 p.)
• Collana: Ciba Foundation symposium ; ; 93
• Disciplina: 574.87/328; 574.87328
• Soggetti: Nucleic acids; Proteins
• Lingua di pubblicazione: Inglese
• Formato: Materiale a stampa
• Livello bibliografico: Monografia
• Note generali: Description based upon print version of record.
• Nota di bibliografia: Includes bibliographical references and indexes.
• Nota di contenuto: Mobility and J function in proteins and nucleic acids; Contents; Introduction; The role of mobility in the substrate binding and catalytic machinery of enzymes; Discussion; Ligand- induced conformational changes in proteins; Discussion; Mobility and active-site coupling in 2-0x0 acid dehydrogenase complexes; Discussion; The mobility of calcium- trigger proteins and its function; Discussion; Mobility and function in elastin and collagen; Discussion; Flexibility in tobacco mosaic virus; Discussion; The molecular basis of muscle contraction; Discussion; Actin-induced changes in the dynamics of myosin subfragment-1 detected by nuclear magnetic resonance Discussion; Rotational dynamics of spin-labelled muscle proteins; Discussion; Cross-bridge movement in muscle and the conformation of the myosin hinge; Discussion; Nuclear magnetic resonance studies on structure and breathing dynamics of transfer RNA; Discussion; Triplet anisotropy ; decay measurements of DNA internal motion; Discussion; Conformations and flexibilities of histones and high mobility group (HMG) proteins in chromatin structure and function; Discussion; Local and collective motions in protein dynamics Discussion; Soliton theory of protein dynamics; Discussion; Nuclear magnetic resonance studies of mobility in proteins; Discussion; Summary and outlook; FINAL GENERAL DISCUSSION; Closing remarks; Index of contributors; Subject index
• Sommario/riassunto: The Novartis Foundation Series is a popular collection of the proceedings from Novartis Foundation Symposia, in which groups of leading scientists from a range of topics across biology, chemistry and medicine assembled to present papers and discuss results. The Novartis Foundation, originally known as the Ciba Foundation, is well known to scientists and clinicians around the world.