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Record Nr. |
UNINA9910827447303321 |
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Titolo |
Mammalian cell biotechnology in protein production / / editors, Hansjörg Hauser, Roland Wagner |
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Pubbl/distr/stampa |
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Berlin ; ; New York, : Walter de Gruyter, 1997 |
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ISBN |
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Edizione |
[1st ed.] |
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Descrizione fisica |
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1 online resource (512 p.) |
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Classificazione |
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Altri autori (Persone) |
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HauserHansjörg <1949-> |
WagnerRoland <1956-> |
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Disciplina |
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Soggetti |
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Proteins - Biotechnology |
Animal cell biotechnology |
Mammals - Cytology |
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Lingua di pubblicazione |
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Formato |
Materiale a stampa |
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Livello bibliografico |
Monografia |
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Note generali |
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Bibliographic Level Mode of Issuance: Monograph |
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Nota di bibliografia |
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Includes bibliographical references and index. |
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Nota di contenuto |
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Frontmatter -- Preface -- Contents -- Contributors List -- 1. Genetic Manipulation of Mammalian Cells -- 1.1 Heterologous Expression of Genes in Mammalian Cells / Hauser, Hansjörg -- 1.2 Permanent Gene Expression in Mammalian Cells: Gene Transfer And Selection / Schlokat, Uwe / Himmelspach, Michèle / Falkner, Falko G. / Dorner, Friedrich -- 1.3 Vectors for Gene Transfer and Expression in Animal Cells / Sandig, Volker / Lieber, Andre / Strauss, Michael -- 1.4 Aspects of Gene Transfer and Gene Amplification in Recombinant Mammalian Cells / Wurm, Florian Μ. -- 1.5 Isolation of Recombinant Cell Clones Exhibiting High-Level Expression of the Introduced Gene / Wirth, Manfred -- 1.6 Genetic Engineering of Antibodies and Derivatives from Mammalian Cells / Schäffner, Michaela / Kaluza, Brigitte / Weidle, Ulrich Η. -- 1.7 Safety Evaluation of Products Derived From Mammalian Cell Lines / Onions, David -- 2. Biological Aspects of Animal Cells -- 2.1 Metabolic Control of Animal Cell Culture Processes / Wagner, Roland -- 2.2 Glycosylation: A Post-Translational Modification / Savage, Angela -- 3. Cell Cultivation Technology -- 3.1 Bioreactors Designed for Animal Cells / Tokashiki, Michiyuki / Yokoyama, Seiichi -- 3.2 Hydrodynamic Properties in Bioreactors / Chattopadhyay, Devamita |
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/ Garcia-Briones, Miguel / Venkat, Raghavan / Chalmers, Jeffrey J. -- 3.3 Kinetics and Simulation of Animal Cell Processes / Goergen, Jean-Louis / Marc, Annie / Engasser, Jean-Marc -- 3.4 On-line and Off-line Process Analysis / Scheper, Thomas / Freitag, Ruth / Scrienc, Friedrich -- 4. Down-Stream Processing -- 4.1 Principles of Product Extraction from Cell Culture and Purification for Pharmaceutical Proteins / Jungbauer, Alois -- 4.2 Validation of Downstream Processes / Walter, Joachim / Allgaier, Hermann -- Index -- Backmatter |
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Sommario/riassunto |
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"Hauser and Wagner have presented the new possibilities of Mammalian Cell Biology in a very informative and stimulating manner." Prof. Dr. Hans Fritz, Ludwig-Maximilians-University Munich |
"Hauser und Wagner haben die neuen Möglichkeiten der Mammalian Cell Biology sehr anregend dargestellt."Prof. Dr. Hans Fritz, Ludwig-Maximilians-Universität München |
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