1.

Record Nr.

UNINA9910826813103321

Autore

Hackshaw Allan K

Titolo

A concise to clinical trials / / Allan Hackshaw

Pubbl/distr/stampa

Oxford, : Wiley-Blackwell, c2009

ISBN

1-4443-5666-6

1-282-13959-2

9786612139598

1-4443-1172-7

1-4443-1171-9

Edizione

[1st ed.]

Descrizione fisica

1 online resource (225 p.)

Disciplina

615.19

615.50724

Soggetti

Clinical trials

Clinical medicine - Research

Lingua di pubblicazione

Inglese

Formato

Materiale a stampa

Livello bibliografico

Monografia

Note generali

Description based upon print version of record.

Nota di bibliografia

Includes bibliographical references and index.

Nota di contenuto

A Concise Guide to Clinical Trials; Contents; Preface; Foreword; 1 Fundamental concepts; 2 Types of outcome measures and understanding them; 3 Design and analysis of phase I trials; 4 Design and analysis of phase II trials; 5 Design of phase III trials; 6 Randomisation; 7 Analysis and interpretation of phase III trials; 8 Systematic reviews and meta-analyses; 9 Health-related quality of life and health economic evaluation; 10 Setting up, conducting and reporting trials; 11 Regulations and guidelines; Reading list; Statistical formulae for calculating some 95% confidence intervals; Index

Sommario/riassunto

Clinical trials have revolutionized the way disease is prevented, detected and treated, and early death avoided, and they continue to be an expanding area of research. They are central to the work of pharmaceutical companies, and there are many academic and public sector organizations that conduct trials on a wide variety of interventions, including drugs, devices, surgical techniques, and changes in behaviour and lifestyle. A Concise Guide to Clinical Trials provides a comprehensive yet easy-to-read overview of the design, conduct and analysis of trials. It requires no prior