1.

Record Nr.

UNINA9910826273803321

Autore

Feitelson Mark

Titolo

Hepatitis C virus : from laboratory to clinic / / Mark A. Feitelson

Pubbl/distr/stampa

Cambridge, UK ; ; New York, : Cambridge University Press, 2002

ISBN

1-107-12231-7

1-280-16221-X

9786610162215

0-511-11919-4

0-511-04132-2

0-511-15734-7

0-511-30447-1

0-511-54532-0

0-511-04734-7

Edizione

[1st ed.]

Descrizione fisica

1 online resource (xiv, 256 pages) : digital, PDF file(s)

Disciplina

616.3/623

Soggetti

Hepatitis C

Hepatitis C virus

Lingua di pubblicazione

Inglese

Formato

Materiale a stampa

Livello bibliografico

Monografia

Note generali

Title from publisher's bibliographic system (viewed on 05 Oct 2015).

Nota di bibliografia

Includes bibliographical references (p. 177-247) and index.

Nota di contenuto

Cover; Half-title; Title; Copyright; Dedication; Contents; Preface; Foreword; Abbreviations; Part I Basic principles; Part II Recent advances; Part III Experimental approaches; Part IV Protocols and techniques; Part V Some outstanding questions and emerging areas for investigation; References; Index

Sommario/riassunto

Hepatitis C infects 170 million people worldwide, and has been labelled the 'silent epidemic' as a result of its concealed attack on the liver. This multidisciplinary overview covers basic concepts related to the discovery of the virus, development of serological and nucleic acid tests to detect infection, the structure of the virus genome, generation of virus gene products, and proposed replication scheme. It then goes on to introduce the epidemiology, transmission, pathogenesis of infection, the development of hepatocellular carcinoma associated with chronic virus infection, and current strategies for treatment. The book then



discusses advances in cell culture systems, animal models of infection, and emerging treatments and vaccine development. Through its coverage of basic science, clinical consequences, and methods of research, this integrated and accessible account will be of immense value to biomedical scientists and clinicians alike, and a useful introduction for all those studying the virus and its effects.