| |
|
|
|
|
|
|
|
|
1. |
Record Nr. |
UNINA9910825567803321 |
|
|
Titolo |
Galectins / / edited by Anatole A. Klyosov, Zbigniew J. Witczak, David Platt |
|
|
|
|
|
|
|
Pubbl/distr/stampa |
|
|
Hoboken, N.J., : John Wiley & Sons, c2008 |
|
|
|
|
|
|
|
ISBN |
|
1-281-38211-6 |
9786611382117 |
0-470-37807-7 |
0-470-37778-X |
|
|
|
|
|
|
|
|
Edizione |
[1st ed.] |
|
|
|
|
|
Descrizione fisica |
|
1 online resource (302 p.) |
|
|
|
|
|
|
Altri autori (Persone) |
|
KlesovA. A (Anatolii Alekseevich) |
WitczakZbigniew J. <1947-> |
PlattDavid <1953-> |
|
|
|
|
|
|
|
|
Disciplina |
|
|
|
|
|
|
Soggetti |
|
|
|
|
|
|
|
|
Lingua di pubblicazione |
|
|
|
|
|
|
Formato |
Materiale a stampa |
|
|
|
|
|
Livello bibliografico |
Monografia |
|
|
|
|
|
Note generali |
|
Description based upon print version of record. |
|
|
|
|
|
|
Nota di bibliografia |
|
Includes bibliographical references and index. |
|
|
|
|
|
|
Nota di contenuto |
|
GALECTINS; CONTENTS; Preface; Contributors; 1 Stumbling on Galectins; 2 Galectins and Their Functions in Plain Language; 3 Understanding Galectin Structure-Function Relationships to Design Effective Antagonists; 4 Galectins as Regulators of Tumor Growth and Invasion by Targeting Distinct Cell Surface Glycans and Implications for Drug Design; 5 Nuclear and Cytoplasmic Localization of Galectin-1 and Galectin-3 and Their Roles in Pre-mRNA Splicing; 6 Galectins in Regulation of Inflammation and Immunity |
7 Galectins as Danger Signals in Host-Pathogen and Host-Tumor Interactions: New Members of the Growing Group of ""Alarmins""?8 The Role of Galectins in Organ Fibrosis; 9 Galectin-1, Cancer Cell Migration, Angiogenesis, and Chemoresistance; 10 Galectin-3 in the Progression and Metastasis of Colorectal Neoplasia; 11 Galectins in Malignant Gliomas: Expression, Functions, and Possible Therapeutic Options; 12 Food-Related Carbohydrate Ligands for Galectins; Index |
|
|
|
|
|
|
|
|
Sommario/riassunto |
|
The comprehensive guide to the current understanding of galectins and their promising potential in drug design This is the first book focusing |
|
|
|
|
|
|
|
|
|
|
on galectins. It was inspired by topics discussed at the symposium ""Galectins: Structures, Functions, and Therapeutic Targets"" that was a part of the 234th American Chemical Society meeting in 2007. To help chemists, biochemists, and others understand the challenges inherent in the study of galectins and build on recent advances in the field, the editors have compiled articles from leading experts on galectins and their biomedical applications. |
|
|
|
|
|
| |