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Record Nr. |
UNINA9910825510403321 |
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Titolo |
Aging in today's environment / / Committee on Chemical Toxicity and Aging, Board on Environmental Studies and Toxicology, Commission on Life Sciences, National Research Council |
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Pubbl/distr/stampa |
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Washington, D.C., : National Academy Press, 1987 |
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ISBN |
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1-280-18635-6 |
9786610186358 |
0-309-56748-3 |
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Edizione |
[1st ed.] |
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Descrizione fisica |
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1 online resource (234 p.) |
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Altri autori (Persone) |
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ButlerRobert N. <1927-2010.> |
PfitzerEmil A |
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Disciplina |
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Soggetti |
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Older people - Effect of environment on |
Aging |
Environmental health |
Human beings - Effect of environment on |
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Lingua di pubblicazione |
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Formato |
Materiale a stampa |
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Livello bibliografico |
Monografia |
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Note generali |
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Committee chairmen: Robert N. Butler and Emil A. Pfitzer. |
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Nota di bibliografia |
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Includes bibliographical references (p. 171-208). |
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Nota di contenuto |
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AGING In Today's Environment; Copyright; Preface; Contents; Executive Summary; AGING AND NUTRITION; AGING AND SUSCEPTIBILITY TO DISEASE; AGING, DISEASE, PHARMACEUTICAL USE, AND CHEMICAL RESPONSE; AGING AND ENVIRONMENTAL FACTORS; MODEL SYSTEMS FOR RESEARCH; CONCLUSIONS; 1 Aging and Environmental Exposure ; BASIS OF THE SCIENTIFIC PROBLEM; STRUCTURE OF THE REPORT; 2 The Aging Population and the Psychosocial Implications of Aging ; DEMOGRAPHIC CONSIDERATIONS OF AN AGING POPULATION; PSYCHOSOCIAL ENVIRONMENT; 3 Principles of Gerontology ; CONCEPTUAL CONTEXT OF GERONTOLOGY; THEORIES OF AGING |
Deterministic TheoriesDevelopmental Switches in Gene Expression; Neuroendocrine-Cascade Theories; Stochastic Theories; Intrinsic Mutagenesis Theory; Protein-Synthesis Error Catastrophe; Free Radicals; Posttranslational Glycation of Proteins and DNA; Thymic Involution as a Pacemaker of Immunosenescence; BIOMARKERS OF AGE OR AGING; ALTERED SUSCEPTIBILITY OF THE AGED; 4 Principles of |
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Toxicology in the Context of Aging ; CHEMICAL FATE AND EFFECT; Absorption; Distribution; Metabolism and Elimination; MECHANISMS OF TOXICITY AT THE MOLECULAR, CELLULAR, AND TISSUE LEVEL; Molecular Action |
Cellular EffectsEffects at the Tissue Level; PHARMACOGENETICS; BIOLOGIC MARKERS; TOXICITY TESTING; 5 Characteristics of the Environment, Aging, and the Aged ; NUTRITION; Effects of Nutrition on Toxicity; Nutrition and Cancer; Nutrition and Aging; Background and Criteria for Evaluating Aging; Food Restriction; Dietary Protein Intake; Dietary Fat Intake; Dietary Carbohydrate Intake; Dietary Vitamin Intake; Dietary Mineral Intake; Special Dietary Requirements of the Aged; PHARMACEUTICALS; Demographic Considerations; Patterns of Drug Use and Drug Prescribing; Ambulatory Populations |
Hospital PopulationsLong-Term-Care Facilities; Medication Compliance in the Elderly; Adverse Drug Reactions; LIFE-STYLE; Deliberate Chemical Exposure; Learned Helplessness; Atrophy of Disuse; Indoor Pollutants; Temperature; Radon; Formaldehyde; Combustion Products; Asbestos; Environmental Tobacco Smoke; Pesticides; 6 Environmental Effects on Age-Associated Diseases and Changes in Organ Function ; DEMOGRAPHICS OF AGE-ASSOCIATED DISEASES; SKIN; VISION; Cataracts; Glaucoma; Diabetic Retinopathy; Aging-Related Macular Degeneration; HEARING; NERVOUS SYSTEM; Changes Associated with Aging |
Induced Disorders and DiseasesNeurotoxicants; RESPIRATORY SYSTEM; CARDIOVASCULAR SYSTEM; RENAL SYSTEM; IMMUNE SYSTEM; SEXUALITY; ROLE OF ENVIRONMENT IN BONE METABOLISM AND VITAMIN D NUTRITION; 7 Model Systems for the Evaluation of Toxic Agents Affecting Aging or Age-Related Diseases ; CONSIDERATIONS IN CHOOSING AND DESIGNING MODEL SYSTEMS; EXAMPLES OF MODEL SYSTEMS; In Vitro Models; Nonmammalian Animal [Models; Mammalian Models; Epidemiologic Models; LIFE-SPAN MODULATION BY DRUG TREATMENT; 8 Conclusions ; 9 Recommendations ; RESEARCH; EDUCATION; FUNDING AND RESOURCES; References |
Appendix Resources for Studying Aging |
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