1.

Record Nr.

UNINA9910824706003321

Titolo

Nanotechnology in diagnosis, treatment and prophylaxis of infectious diseases / / edited by Mahendra Rai, Biotechnology Department, SGB Amravati University, Amravati, Maharashtra, India, Kateryna Kon, Department of Microbiology, Virology and Immunology, Kharkiv National Medical University, Kharkiv, Ukraine

Pubbl/distr/stampa

Amsterdam : , : Elsevier, , [2015]

©2015

ISBN

0-12-801317-6

Descrizione fisica

1 online resource (361 p.)

Disciplina

612.8252

Soggetti

Nanotechnology - Health aspects

Medical technology

Nanomedicine

Communicable diseases

Lingua di pubblicazione

Inglese

Formato

Materiale a stampa

Livello bibliografico

Monografia

Note generali

Description based upon print version of record.

Nota di bibliografia

Includes bibliographical references and index.

Nota di contenuto

""Front Cover""; ""Nanotechnology in Diagnosis, Treatment and Prophylaxis of Infectious Diseases""; ""Copyright Page""; ""Contents""; ""List of Contributors""; ""Preface""; ""1 Gold and Silver Nanoparticles for Diagnostics of Infection""; ""1.1 Nanotechnology and Infection""; ""1.2 Gold and Silver NPs for Molecular Diagnostics""; ""1.2.1 Biomarkers""; ""1.3 Nanodiagnostics for Nucleic Acids""; ""1.3.1 Homogeneous Colorimetric Assays""; ""1.3.1.1 Unmodified NPs""; ""1.3.1.2 Cross-Linking""; ""1.3.1.3 Noncross-Linking""; ""1.3.2 Heterogeneous Detection""; ""1.3.2.1 Microarrays""

""1.3.2.2 Lateral Flow Assays""""1.3.3 Electrochemical Assays""; ""1.3.4 Fluorescence Assays""; ""1.3.5 Raman and SERS""; ""1.3.6 Other""; ""1.4 Aptamers and Antibodies""; ""1.4.1 Colorimetric""; ""1.4.2 Electrochemical""; ""1.4.3 Lateral Flow Assays""; ""1.5 iPCR and Other Methods""; ""1.6 Conclusion""; ""References""; ""2 Antimicrobial Models in Nanotechnology: From the Selection to Application in the Control and Treatment of Infectious Diseases""; ""2.1 Introduction""; ""2.2



Antimicrobial Susceptibility Testing Methods of NMs""; ""2.2.1 Broth Dilution Test""

""2.2.2 Spectrophotometric Measurement""""2.2.3 Cell Counting""; ""2.2.4 Colorimetric and Fluorescent Assays""; ""2.2.5 In Vitro Infection Animal Model""; ""2.2.6 Biocidal Testing""; ""2.2.7 Antibiofilm Activity""; ""2.2.8 Quorum-Sensing Inhibitors""; ""2.2.9 Microbial Membrane Lysis""; ""2.2.10 Microbial Oxidative Stress""; ""2.2.11 Antipersister and Antidormancy Bacterial Cells""; ""2.2.12 Microbial Fitness""; ""2.3 Nanotoxicology""; ""2.3.1 Nano-Genotoxicology""; ""2.3.2 Cytotoxicity""; ""2.3.3 Immunotoxicity""; ""2.3.4 In Vitro Skin Irritation""

""2.3.5 Caenorhabditis elegans Toxicity Model""""2.3.6 Nanotoxicity in Embryonic and Adult Zebrafish""; ""2.3.7 Bioluminescence-Based Nanotoxicity Test""; ""2.4 In Vitro Pharmacokinetics/Pharmacodynamic Models""; ""2.4.1 Particokinetics""; ""2.4.2 Caco-2 Permeability""; ""2.4.3 Hollow Fiber System""; ""2.5 Conclusions""; ""References""; ""3 Silver Nanoparticles for the Control of Vector-Borne Infections""; ""3.1 Introduction""; ""3.2 Louse-Borne Infections and Activity of AgNPs Against Lice""; ""3.3 Mosquito-Borne Infections and Activity of AgNPs Against Mosquitoes""

""3.4 Tick-Borne Infections and Activity of AgNPs Against Ticks""""3.5 Flies, Their Role in Transmission and Spread of Infections, and Activity of AgNPs Against Flies""; ""3.6 Conclusions and Future Prospects""; ""References""; ""4 Magnetite Nanostructures: Trends in Anti-Infectious Therapy""; ""4.1 Introduction""; ""4.2 Nanoparticles with Biomedical Applications""; ""4.2.1 Design of Tailored Magnetic Nanoparticles with Applications in Microbiology""; ""4.2.2 Magnetite Nanoparticles Used to Control Microorganisms Attachment and Biofilm Formation""

""4.2.3 The Biocompatibility of Magnetite Nanoparticles""

Sommario/riassunto

Nanotechnology in Diagnosis, Treatment and Prophylaxis of Infectious Diseases delivers comprehensive coverage of the application of nanotechnology to pressing problems in infectious disease.    This text equips readers with cutting-edge knowledge of promising developments and future prospects in nanotechnology, paying special attention to microbes that are now resistant to conventional antibiotics, a concerning problem in modern medicine.    Readers will find a thorough discussion of this new approach to infectious disease treatment, including the reasons nanotechnology presents a promising