1.

Record Nr.

UNINA9910824268103321

Autore

Ferrer Imma <1970->

Titolo

Liquid chromatography/time-of-flight mass spectrometry : principles, tools, and applications for accurate mass analysis / / Imma Ferrer, E.M. Thurman

Pubbl/distr/stampa

Hoboken, NJ, : Wiley, 2008

ISBN

1-282-11306-2

9786612113062

0-470-42996-8

0-470-42995-X

Edizione

[1st ed.]

Descrizione fisica

1 online resource (281 p.)

Collana

Chemical Analysis: A Series of Monographs on Analytical Chemistry and Its Applications ; ; v.254

Altri autori (Persone)

ThurmanE. M <1946-> (Earl Michael)

Disciplina

543.84

543/.84

Soggetti

Liquid chromatography

Time-of-flight mass spectrometry

Lingua di pubblicazione

Inglese

Formato

Materiale a stampa

Livello bibliografico

Monografia

Note generali

Includes index.

Nota di contenuto

LIQUID CHROMATOGRAPHY TIME-OF-FLIGHT MASS SPECTROMETRY; CONTENTS; PREFACE; CONTRIBUTORS; PART I PRINCIPLES AND THEORETICAL ASPECTS OF ACCURATE MASS; CHAPTER 1 ACCURATE MASS MEASUREMENTS WITH ORTHOGONAL AXIS TIME-OF-FLIGHT MASS SPECTROMETRY; CHAPTER 2 THE MASS DEFECT, ISOTOPE CLUSTERS, AND ACCURATE MASS FOR ELEMENTAL DETERMINATION; PART II TOOLS FOR UNKNOWN IDENTIFICATION USING ACCURATE MASS; CHAPTER 3 ION COMPOSITIONS DETERMINED WITH INCREASING SIMPLICITY; CHAPTER 4 EXISTENCE AND USE OF ACCURATE MASS DATABASES AND ELEMENTAL COMPOSITION TOOLS FOR TARGET AND NON-TARGET ANALYSES

CHAPTER 5 USE OF UPLC-(Q)TOF MS FOR RAPID SCREENING OF ORGANIC MICROPOLLUTANTS IN WATER CHAPTER 6 THE USE OF ACCURATE MASS, ISOTOPE RATIOS, AND MS/MS FOR THE ANALYSIS OF PPCPs IN WATER; PART III APPLICATIONS OF LC/TOF-MS FOR THE IDENTIFICATION OF SMALL MOLECULES; CHAPTER 7 APPLICATIONS OF



LC/TOF-MS IN THE ENVIRONMENTAL FIELD: WHEN DID IT START AND WHERE IS IT GOING?; CHAPTER 8 LIQUID CHROMATOGRAPHY AND AMBIENT IONIZATION TIME-OF-FLIGHT MASS SPECTROMETRY FOR THE ANALYSIS OF GENUINE AND COUNTERFEIT PHARMACEUTICALS

CHAPTER 9 QUANTITATIVE ANALYSIS OF VETERINARY DRUG RESIDUES BY SUB 2-μm PARTICULATE HIGH-PERFORMANCE LIQUID CHROMATOGRAPHY COLUMNS AND TIME-OF-FLIGHT MASS SPECTROMETRY (UPLC-TOF)CHAPTER 10 INDUSTRIAL APPLICATIONS OF LIQUID CHROMATOGRAPHY TIME-OF-FLIGHT MASS SPECTROMETRY; CHAPTER 11 COMPREHENSIVE TOXICOLOGICAL AND FORENSIC DRUG SCREENING BY LC/TOF-MS; CHAPTER 12 APPLICATION OF UPLC/TOF-MS FOR RESIDUE ANALYSIS OF VETERINARY DRUGS AND GROWTH-PROMOTING AGENTS IN PRODUCTS OF ANIMAL ORIGIN

CHAPTER 13 ACCURATE MASS MEASUREMENTS WITH A REFLECTRON TIME-OF-FLIGHT MASS SPECTROMETER AND THE DIRECT ANALYSIS IN REAL TIME (DART) INTERFACE FOR THE IDENTIFICATION OF UNKNOWN COMPOUNDS BELOW MASSES OF 500 DACHAPTER 14 COMPARISON OF LC/TOF-MS AND LC/MS-MS FOR THE ANALYSIS OF 100 PESTICIDES IN FOOD: FINDING THE "CROSSOVER POINT""; INDEX

Sommario/riassunto

Time of flight mass spectrometry identifies the elements of a compound by subjecting a sample of ions to a strong electrical field. Illuminating emerging analytical techniques in high-resolution mass spectrometry, Liquid Chromatography Time-of-Flight Mass Spectrometry shows readers how to analyze unknown and emerging contaminants-such as antibiotics, steroids, analgesics-using advanced mass spectrometry techniques. The text combines theoretical discussion with concrete examples, making it suitable for analytical chemists, environmental chemists, organic chemists, medicinal chemists,