The glutamate receptors / / edited by Robert W. Gereau, Geoffrey T. Swanson

• Record Nr.: UNINA9910824105003321
• Pubbl/distr/stampa: Totowa, N.J., : Humana Press, c2008
• ISBN: 1-281-22023-X; 9786611220235; 1-59745-055-3
• Edizione: [1st ed. 2008.]
• Descrizione fisica: 1 online resource (587 p.)
• Collana: The receptors
• Altri autori (Persone): GereauRobert W; SwansonGeoffrey
• Disciplina: 612.8042; 612.81
• Soggetti: Glutamic acid - Receptors; Proteins
• Lingua di pubblicazione: Inglese
• Formato: Materiale a stampa
• Livello bibliografico: Monografia
• Note generali: Description based upon print version of record.
• Nota di bibliografia: Includes bibliographical references and index.
• Nota di contenuto: AMPA Receptors -- NMDA Receptors -- Kainate Receptors -- Delta Receptors -- Ionotropic Glutamate Receptors in Synaptic Plasticity -- Structural Correlates of Ionotropic Glutamate Receptor Function -- Positive Modulators of AMPA-Type Glutamate Receptors -- Clinically Tolerated Strategies for NMDA Receptor Antagonism -- The Structures of Metabotropic Glutamate Receptors -- Group I Metabotropic Glutamate Receptors (mGlu1 and mGlu5) -- Group II Metabotropic Glutamate Receptors (mGlu2 and mGlu3) -- Group III Metabotropic Glutamate Receptors (mGlu4, mGlu6, mGlu7, and mGlu8) -- Metabotropic Glutamate Receptor-Dependent Synaptic Plasticity -- Metabotropic Glutamate Receptor Ligands as Novel Therapeutic Agents.
• Sommario/riassunto: Glutamate receptors are critically important for normal brain function. The preceding decade has seen remarkable advances in our understanding of the physiological function and molecular structure of these proteins. The Glutamate Receptors provides an expansive review of the field with a topical update to two excellent books - The Ionotropic Glutamate Receptors and The Metabotropic Glutamate Receptors. An exciting primer to the study of glutamate receptors and ; their central role in neurotransmission, The Glutamate Receptors covers the extraordinary research and significant developments in the decade since the previous books were published and gives a snapshot of how prominent scientists look to the future of research in the field. Both insightful and comprehensive, The Glutamate Receptors provides an invaluable reference to students and scientists on nearly every aspect of glutamate receptor structure and function.