1.

Record Nr.

UNINA9910824017603321

Autore

Yang Ziheng

Titolo

Computational molecular evolution / / Ziheng Yang

Pubbl/distr/stampa

Oxford, : Oxford University Press, 2006

ISBN

1-280-84627-5

0-19-151376-8

1-4294-5951-4

Edizione

[1st ed.]

Descrizione fisica

1 online resource (374 p.)

Collana

Oxford series in ecology and evolution

Disciplina

572.838015118

Soggetti

Molecular evolution - Mathematical models

Molecular evolution - Data processing

Lingua di pubblicazione

Inglese

Formato

Materiale a stampa

Livello bibliografico

Monografia

Note generali

Description based upon print version of record.

Nota di bibliografia

Includes bibliographical references (p. [319]-352) and index.

Nota di contenuto

Contents; PART I: MODELLING MOLECULAR EVOLUTION; 1 Models of nucleotide substitution; 2 Models of amino acid and codon substitution; PART II: PHYLOGENY RECONSTRUCTION; 3 Phylogeny reconstruction: overview; 4 Maximum likelihood methods; 5 Bayesian methods; 6 Comparison of methods and tests on trees; PART III: ADVANCED TOPICS; 7 Molecular clock and estimation of species divergence times; 8 Neutral and adaptive protein evolution; 9 Simulating molecular evolution; 10 Perspectives; Appendices; A: Functions of random variables; B: The delta technique; C: Phylogenetics software; References; Index; A

BC; D; E; F; G; H; I; J; K; L; M; N; O; P; Q; R; S; T; U; W; Y

Sommario/riassunto

This book describes the models, methods and algorithms that are most useful for analysing the ever-increasing supply of molecular sequence data, with a view to furthering our understanding of the evolution of genes and genomes. - ;The field of molecular evolution has experienced explosive growth in recent years due to the rapid accumulation of genetic sequence data, continuous improvements to computer hardware and software, and the development of sophisticated analytical methods. The increasing availability of large genomic data sets requires powerful statistical methods to analyse and interpr