1.

Record Nr.

UNINA9910823388403321

Titolo

The laboratory rabbit, guinea pig, hamster, and other rodents [[electronic resource] /] / edited by Mark A. Suckow, Karla A. Stevens, Ronald P. Wilson

Pubbl/distr/stampa

London, : Elsevier, 2012

ISBN

1-283-39404-9

9786613394040

0-12-380921-5

Edizione

[1st ed.]

Descrizione fisica

1 online resource (1289 p.)

Collana

American College of Laboratory Animal Medicine series

Altri autori (Persone)

SuckowMark A

StevensKarla A

WilsonRonald P

Disciplina

636.0885

636.932

Soggetti

Laboratory animals

Rabbits as laboratory animals

Guinea pigs as laboratory animals

Hamsters as laboratory animals

Lingua di pubblicazione

Inglese

Formato

Materiale a stampa

Livello bibliografico

Monografia

Note generali

Description based upon print version of record.

Nota di bibliografia

Includes bibliographical references and index.

Nota di contenuto

Front Cover; The Laboratory Rabbit, Guinea Pig, Hamster, and Other Rodents; Copyright Page; Contents; Preface; List of Contributors; List of Reviewers; I. GENERAL; 1. Ethical Considerations and Regulatory Issues; Introduction; Ethical Concepts; Moral Theories; Descriptive Laboratory Animal Use Ethics; Ethical Principles; Respect for Life; Societal Benefit; Non-Maleficence; The Three Rs (Replacement, Reduction, and Refinement); Replacement; Reduction; Refinement; Ethical Challenges; Breeding Colonies; Genetically Modified Rodents; Cancer Research; Perinatal Animal Use

Neuroscience and Behavioral ResearchFood and Fluid Restriction; Neuroanatomic Studies; Neural Injury and Disease; Behavioral Studies; Prolonged Restraint and Anesthesia; Restraint of Awake Animals; Prolonged Studies in Anesthetized Animals; Institutional Animal Welfare Oversight; Regulations and Non-regulatory Considerations; United



States Regulatory Considerations; United States Animal Welfare Act; Public Health Service Policy on Humane Care and Use of Animals; Food and Drug Administration Good Laboratory Practices; Interagency Cooperation

Environmental Protection Agency Good Laboratory PracticesNon-Regulatory Considerations; Institute for Laboratory Animal Research; Guide for the Care and Use of Laboratory Animals (Guide); International Regulations, Policies, and Standards; AAALAC, International; Canada; European Union; Pacific Rim; Australia; New Zealand; Japan; South Korea; Philippines; Thailand; China; Taiwan; Singapore; Hong Kong; Conclusion; References; 2. Anesthesia and Analgesia; Pre-anesthetic Preparation; Physical Examination; Fasting; Stabilization; Regulatory Requirements; Controlled Substances; Pharmacology

AnticholinergicsPhenothiazines; Benzodiazepines; Alpha2-Agonists; Systemic Analgesics; Opioids; Non-Steroidal Anti-Inflammatory Drugs (NSAIDs); Tramadol; Gabapentin; Amantadine; Local Anesthetics; Glucocorticoids; N-Methyl-D-Aspartic Acid (NMDA) Antagonist; Ketamine; Tiletamine-Zolazepam; Propofol; Barbiturates; Inhalation Anesthetics; Anesthesia Circuits; Induction Chambers; Breathing Circuits; Vaporizer Types and Machines; Ventilators; Regulatory Monitoring Requirements; Anesthesia Waste Gas Scavenging; Anesthesia Monitoring and Support; Anesthetic Depth; Respiratory Function

Cardiovascular FunctionTemperature; Fluid Therapy; Intubation; Surgical Anesthesia; Post-operative Monitoring and Pain Assessment; Pain Assessment; Post-Operative Analgesia; Post-Operative Monitoring; References; 3. Clinical Biochemistry and Hematology; Introduction; Clinical Biochemistry; Introduction; Sample Collection; Restraint; Blood Collection; Urine Collection; Carbohydrate Metabolism; Glucose; Lipid Metabolism; Cholesterol; Triglycerides; Enzymes; Alkaline Phosphatase (ALP); Alanine Aminotransferase (ALT); Aspartate Aminotransferase (AST); Lactate Dehydrogenase (LDH)

Creatine Kinase (CK)

Sommario/riassunto

The Laboratory Rabbit, Guinea Pig, Hamster, and Other Rodents is a single volume, comprehensive book sanctioned by the American College of Laboratory Animal Medicine (ACLAM), covering the rabbit, guinea pig, hamster, gerbil and other rodents often used in research. This well-illustrated reference won a 2012 PROSE Award for Best Single Volume Reference in Science from the Association of American Publishers. The book includes basic biology, anatomy, physiology, behavior, infectious and noninfectious diseases, husbandry and breeding, common experimental methods, and use of the species as a