Hormonal regulation of farm animal growth / / K.L. Hossner

• Record Nr.: UNINA9910823374003321
• Autore: Hossner K. L (Kim L.)
• Pubbl/distr/stampa: Wallingford, Oxfordshire, UK ; ; Cambridge, MA, : CABI Pub., c2005
• ISBN: 1-280-73558-9; 9786610735587; 1-84593-090-8
• Edizione: [1st ed.]
• Descrizione fisica: 1 online resource (231 p.)
• Disciplina: 636.08/52
• Soggetti: Growth regulators; Hormones; Livestock - Growth - Regulation
• Lingua di pubblicazione: Inglese
• Formato: Materiale a stampa
• Livello bibliografico: Monografia
• Note generali: Bibliographic Level Mode of Issuance: Monograph
• Nota di bibliografia: Includes bibliographical references and index.
• Nota di contenuto: Intro -- Contents -- 1 Whole Animal Growth -- Measuring Animal Growth -- Embryonic and Fetal Growth -- Growth Curves -- Genetics, Nutrition and Environmental Effects on Whole Animal Growth -- Genetics -- Nutrition -- Environmental factors -- 2 Cellular and Molecular Biology -- Prokaryotic and Eukaryotic Organisms -- Eukaryotic cell organelles -- The Cell Cycle -- The Central Dogma of Cell Biology -- Eukaryotic genes -- Ribonucleic Acid -- Messenger RNA and translation of protein -- RNA polymerases -- Regulation of gene transcription -- Transcriptional control of specific genes -- Transcription factors -- Biotechnology and Genetic Engineering -- Transgenic Animals and their Potential -- Identifying, Isolating and Transferring Genes -- Homologous recombination, gene targeting and gene knockouts -- 3 The Endocrine System -- Control of Pituitary Hormone Secretion -- Hormone Receptors -- Effector Molecules, Transducers and Second Messengers -- 4 Development of Muscle, Skeletal System and Adipose Tissue -- Embryonic Development and Cell Differentiation -- Cell Proliferation and Differentiation -- The Skeletal System and Bone Growth -- Types of Bones and Gross Anatomy -- Bone Cells and Bone Matrix Formation -- Osteoclasts and bone resorption -- Regulation of osteoclast function -- The Epiphyseal ; Plate -- Skeletal Muscle Development -- Embryonic formation of skeletal muscle -- Skeletal muscle satellite cells -- Myofilaments, Myofibrils and Sarcomeres -- Sarcomeric proteins: actin, myosin and titin -- Myofibres and muscle contraction -- Skeletal Muscle Fibre Types -- Skeletal muscle protein turnover -- The formation of multinucleated skeletal muscle cells -- Adipose Tissue Growth and Development -- Brown adipose tissue -- White adipose tissue -- Adipose tissue development -- Adipose tissue growth: hyperplasia vs hypertrophy -- Lipogenesis and Lipolysis.; 5 Growth Hormone and Insulin-like Growth Factors -- The GH Molecule -- Control of GH secretion -- GH receptors -- Metabolic actions of GH -- Excess and inadequate GH: giants and dwarfs -- IGFs or Somatomedins -- Discovery of the IGFs -- IGF genes and molecules -- IGF receptors -- IGF-binding proteins -- Metabolic effects of the IGFs -- Effects of the IGFs on animal growth -- Modification of the somatomedin hypothesis -- Effects of GH on Farm Animal Production -- GH and the development of transgenic animals -- 6 Calcium Homeostasis and Regulation of Bone Growth -- Hormonal Regulation of Calcium Homeostasis -- Parathyroid hormone -- 1,25-Dihydroxy vitamin D[sub(3)] -- Biological actions of 1,25-dihydroxy vitamin D[sub(3)] -- Calcitonin -- Regulation of Bone Growth and Development -- The hedgehogs and early skeletal differentiation -- Regulation of bone growth and differentiation by hormones -- Growth factors and bone -- FGF -- PDGF -- Transforming growth factor-&amp -- #946 -- -- Bone morphogenetic proteins -- 7 Hormones, Growth Factors and Skeletal Muscle -- Experimental Systems to Study Myogenesis -- Myogenic cell systems -- Muscle Regulatory Factors (MRFs) -- Effects of the MRFs on muscle development -- Regulation of MRF expression -- Growth Factors Affecting Muscle Growth -- IGFs -- Myostatin -- FGF -- TGF-&amp -- #946 -- -- BMPs -- Hepatocyte growth factor -- Hormones regulating muscle growth -- 8 Hormones, Growth Factors and Adipose Tissue -- Cell Systems Used to Study Adipogenesis -- Transcription Factors and Adipogenesis -- PPARs -- C/EBPs -- ADD1/SREBP1 -- Nuclear co-activators and co-repressors: fine-tuning the adipogenic response -- Hormones and Growth Factors Affecting Preadipocytes and Adipocytes -- Insulin -- GH and the IGFs -- Glucocorticoids -- Prostaglandins and cAMP -- Negative Regulators of Adipose Differentiation.; Adipose tissue as an endocrine organ -- 9 Steroids and Animal Growth -- Oestrogens and Ruminant Growth -- Oestrogens and Non-ruminants -- Androgens and Ruminant Growth -- Mechanism of Action of Steroids in Ruminant Growth -- Androgen mechanisms of action -- 10 Catecholamines, Beta-agonists and Nutrient Repartitioning -- The Autonomic Nervous System and the Adrenal Medulla -- Adrenergic Receptors -- &amp -- #946 -- -Adrenergic agonists -- Effects of &amp -- #946 -- -adrenergic agonists on growth and body composition -- 11 Leptin, Body Composition and Appetite Control -- Theories on the Short-term Regulation of Food Intake -- The Long-term Regulation of Food Intake - the Lipostat Theory -- The Discovery of Leptin -- The leptin gene and molecule -- Leptin receptors and binding proteins -- Biological actions of leptin -- Effects of leptin on reproduction -- Direct peripheral effects of leptin -- Regulation of leptin concentrations -- Significance of leptin to animal production -- Appetite-inducing (Orexigenic) Peptides of the Hypothalamus -- Index -- A -- B -- C -- D -- E -- F -- G -- H -- I -- J -- K -- L -- M -- N -- O -- P -- Q -- R -- S -- T -- U -- V -- W -- Z.
• Sommario/riassunto: This book describes the cellular and molecular mechanisms that are involved with the regulation of cell and tissue growth, including ; development and body composition. The emphasis is on circulating hormones, local growth factors and gene transcription factors which regulate growth and differentiation of skeletal muscle, bone and adipose tissue.