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1. |
Record Nr. |
UNISA996538665103316 |
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Autore |
Rojas Ignacio |
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Titolo |
Bioinformatics and Biomedical Engineering [[electronic resource] ] : 10th International Work-Conference, IWBBIO 2023, Meloneras, Gran Canaria, Spain, July 12–14, 2023, Proceedings, Part I / / edited by Ignacio Rojas, Olga Valenzuela, Fernando Rojas Ruiz, Luis Javier Herrera, Francisco Ortuño |
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Pubbl/distr/stampa |
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Cham : , : Springer Nature Switzerland : , : Imprint : Springer, , 2023 |
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ISBN |
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Edizione |
[1st ed. 2023.] |
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Descrizione fisica |
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1 online resource (588 pages) |
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Collana |
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Lecture Notes in Bioinformatics, , 2366-6331 ; ; 13919 |
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Altri autori (Persone) |
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ValenzuelaOlga |
Rojas RuizFernando |
HerreraLuis Javier |
OrtuñoFrancisco |
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Disciplina |
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Soggetti |
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Bioinformatics |
Computer networks |
Engineering—Data processing |
Biomedical engineering |
Computational and Systems Biology |
Computer Communication Networks |
Data Engineering |
Biomedical Engineering and Bioengineering |
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Lingua di pubblicazione |
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Formato |
Materiale a stampa |
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Livello bibliografico |
Monografia |
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Nota di contenuto |
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Intro -- Preface -- Organization -- Contents - Part I -- Contents - Part II -- Analysis of Molecular Dynamics Data in Proteomics -- Recognition of Conformational States of a G Protein-Coupled Receptor from Molecular Dynamic Simulations Using Sampling Techniques -- 1 Introduction -- 2 Materials and Methods -- 2.1 Class Imbalance Correction Methods -- 2.2 Experimental Setup -- 2.3 Evaluation Metrics for Imbalanced Data Problems -- 3 Results and Discussion -- 3.1 Interpretation Results -- 4 Conclusions -- References -- Identification of InhA-Inhibitors Interaction Fingerprints that Affect |
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Residence Time -- 1 Introduction -- 1.1 Ligand-Receptor Binding Kinetics -- 1.2 Computer Methods to Determine Binding Kinetic Parameters -- 1.3 Research Objective -- 2 Mycobacterium Enoyl Acyl Carrier Protein Reductase (InhA) -- 3 Methods -- 4 Results -- 4.1 Ligand Similarity -- 4.2 Drug-Like Ligand Properties that Affect Residence Time -- 5 Discussion and Conclusions -- References -- Bioinformatics -- Validation of Height-for-Age and BMI-for-Age Z-scores Assessment Using Android-Based Mobile Apps -- 1 Introduction -- 2 Methods -- 2.1 Subjects -- 2.2 Anthropometric Measurements -- 2.3 Z-score Calculation -- 2.4 Statistical Analysis -- 3 Outcomes -- 4 Discussion -- 5 Conclusion -- 6 Limitations -- References -- An Algorithm for Pairwise DNA Sequences Alignment -- 1 Introduction -- 2 Related Work -- 3 An Algorithm for Pairwise DNA Sequences Alignment Based on the Proposed CAT Method -- 4 Experimental Results and Analysis -- 4.1 Implementation of the Proposed Method CAT for Sequences Alignment -- 4.2 Collision Analysis -- 4.3 Performance Analysis -- 5 Conclusion -- References -- Multiallelic Maximal Perfect Haplotype Blocks with Wildcards via PBWT -- 1 Introduction -- 2 Finding Maximal Blocks with Wildcards -- 3 The Algorithm. |
3.1 Positional BWT Extended to Wildcards -- 3.2 Building the Extended PBWT -- 3.3 Computing the Maximal Blocks -- 4 Experimental Results -- 5 Conclusions -- References -- GPU Cloud Architectures for Bioinformatic Applications -- 1 Introduction -- 2 GPU Usage in Bioinformatics -- 3 Processing Outsourcing -- 4 GPU Virtualisation in Cloud Architectures -- 5 Architecture Characteristics -- 6 Experiments -- 7 Conclusions -- References -- Biomarker Identification -- Novel Gene Signature for Bladder Cancer Stage Identification -- 1 Introduction -- 2 Data Description -- 3 Metodology -- 3.1 Differential Expressed Genes Extraction and Visualization -- 3.2 Development of Classification Models -- 4 Results and Discussion -- 4.1 Gene Enrichment -- 5 Conclusions -- References -- Predicting Cancer Stage from Circulating microRNA: A Comparative Analysis of Machine Learning Algorithms -- 1 Introduction -- 2 Materials and Methods -- 2.1 Study Cohort -- 2.2 Algorithms -- 2.3 Evaluation Metrics -- 2.4 Experimental Design -- 2.5 Statistical Analysis -- 3 Results -- 4 Discussion -- 5 Conclusion -- 6 Ethical Statement -- 7 Appendix -- References -- Gait Asymmetry Evaluation Using FMCW Radar in Daily Life Environments -- 1 Introduction -- 2 Methodology -- 2.1 Gait Parameters Definition -- 2.2 FMCW Radar Signal Processing -- 2.3 Extraction of Radar-Based Gait Parameters -- 3 Experimental Setup and Equipment -- 4 Experimental Results -- 4.1 Raw Data Visualization -- 4.2 Gait Parameters Extraction Results -- 5 Conclusion and Further Work -- References -- Biomedical Computing -- Whole Tumor Area Estimation in Incremental Brain MRI Using Dilation and Erosion-Based Binary Morphing -- 1 Introduction -- 2 Morphing Methods -- 3 Experiments -- 4 Results -- 5 Conclusions and Discussions -- References. |
Three-Dimensional Representation and Visualization of High-Grade and Low-Grade Glioma by Nakagami Imaging -- 1 Introduction -- 2 Nakagami Imaging -- 3 Highlighting Experiments -- 3.1 High-Grade Glioma Experiment -- 3.2 Low-Grade Glioma Experiment -- 4 Results -- 5 Conclusions and Discussions -- References -- Speeding up Simulations for Radiotherapy Research by Means of Machine Learning -- 1 Introduction -- 2 Problem Description -- 2.1 PENELOPE Simulator -- 3 Methodology: Data Generation with PENELOPE and Modeling the Output by Means of Machine Learning Algorithms -- 3.1 Data Generation -- 3.2 Models Evaluated and Hyperparameter Tunning -- |
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3.3 Implementation Details and Model Deployment -- 4 Experiments and Results -- 4.1 Multi-Output Regression -- 4.2 Single Output Regression -- 5 Conclusions -- References -- A Meta-Graph for the Construction of an RNA-Centered Knowledge Graph -- 1 Introduction -- 2 KG Construction from Bio-Medical Data Sources -- 3 RNA Molecules -- 4 RNA-Based Data Sources -- 5 A Meta-Graph Representing RNA-Centered Relationships -- 6 Concluding Remarks -- References -- Structural Analysis of RNA-Binding Protein EWSR1 Involved in Ewing's Sarcoma Through Domain Assembly and Conformational Molecular Dynamics Studies -- 1 Introduction -- 2 Computational Methodology -- 2.1 Retrieval of Human EWSR1 Sequence and Alignment -- 2.2 EWSR1 Conserved Sequence Analysis -- 2.3 Structure Prediction of Human EWSR1 -- 2.4 Prediction of RNA Motifs Interacting with EWSR1 -- 2.5 Molecular Docking -- 2.6 Molecular Dynamics (MD) Simulations -- 3 Results -- 3.1 Structural Analysis of Predicted EWSR1 -- 3.2 Docking Energy Evaluation -- 3.3 Binding Pocket Conformational and Interaction Analysis -- 3.4 Root Mean Square Deviation Analysis -- 3.5 Radius of Gyration and Solvent Accessible Surface Area -- 4 Conclusion -- References. |
Pharmacoinformatic Analysis of Drug Leads for Alzheimer's Disease from FDA-Approved Dataset Through Drug Repositioning Studies -- 1 Introduction -- 2 Computational Methodology -- 2.1 Retrieval of MADD Sequence and Protein Modelling -- 2.2 Structure Analysis of MADD Protein -- 2.3 Virtual Screening of Chemical Scaffolds -- 2.4 Active Binding Site of MADD Protein and Docking -- 2.5 Designing of Pharmacogenomics Networks -- 2.6 Molecular Dynamics (MD) Simulations -- 3 Results and Discussion -- 3.1 Predicted Model of MADD Protein -- 3.2 VADAR and Galaxy Refine Analysis -- 3.3 Binding Pocket Analysis of MADD Protein -- 3.4 Shape Based Screening and PyRx Docking -- 3.5 Pharmacogenomics Analysis -- 4 Molecular Docking Using Autodock -- 4.1 Docking Energy Analysis Against Death Domain of MADD -- 4.2 Binding Interaction Profile -- 5 Molecular Dynamic Simulations -- 5.1 Root Mean Square Deviation and Rg Analysis -- 6 Conclusions -- References -- Biomedical Engineering -- Motion Control of a Robotic Lumbar Spine Model -- 1 Introduction -- 2 Related Work -- 3 Kinematics -- 4 Dynamic Model -- 5 PID Controller -- 6 Simulation and Results -- 7 Conclusions -- References -- Annotation-Free Identification of Potential Synteny Anchors -- 1 Background -- 2 Theory and Algorithmic Considerations -- 3 Results -- 3.1 Summary Statistics of Anchor Candidates -- 3.2 Evaluation of Anchor Candidates -- 3.3 Mapping of Anchors Candidates Across Genomes -- 3.4 Two Showcase Applications -- 3.5 Computational Effort -- 4 Discussion and Outlook -- A Genomes Used in this Contribution -- References -- Analysing Dose Parameters of Radiation Therapy Treatment Planning and Estimation of Their Influence on Secondary Cancer Risks -- 1 Introduction -- 2 Materials and Methods -- 2.1 Patient Selection -- 2.2 Treatment Planning -- 3 Results and Discussion -- 4 Conclusion -- References. |
A Platform for the Radiomic Analysis of Brain FDG PET Images: Detecting Alzheimer's Disease -- 1 Introduction -- 2 Methods -- 2.1 Participants and Data -- 2.2 PET Acquisition -- 2.3 ROI Extraction -- 2.4 Feature Extraction -- 2.5 Feature Selection -- 2.6 Classification and Tuning -- 2.7 Computational Hardware and Software -- 3 Results -- 4 Discussion -- 5 Conclusion -- References -- Biomedical Signal Analysis -- Deep Learning for Automatic Electroencephalographic Signals Classification -- 1 Introduction -- 2 Methodology -- 2.1 Description of EEG Data -- 2.2 EEG Signal Preprocessing -- 2.3 Feature Extraction -- 2.4 Classification -- 3 Results and Discussions -- 3.1 |
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Evaluation -- 4 Conclusions and Future Work -- References -- Evaluation of Homogeneity of Effervescent Tablets Containing Quercetin and Calcium Using X-ray Microtomography and Hyperspectral Analysis -- 1 Introduction -- 2 Materials and Methods -- 2.1 Tablets Selected for Analysis -- 2.2 Evaluation of the Tablets -- 2.3 Hyperspectral Imaging -- 2.4 X-ray Microtomography -- 2.5 Statistical Analysis -- 3 Results -- 3.1 Characteristics of the Tablets -- 3.2 The Analysis of Tablets' Homogeneity Using Hyperspectral Imaging -- 3.3 The Analysis of Inner Homogeneity Using X-ray Microtomography -- 4 Discussion -- 5 Conclusion -- References -- The Effect of Biofeedback on Learning the Wheelie Position on Manual Wheelchair -- 1 Introduction -- 2 Material and Methods -- 2.1 Subjects and Study Design -- 2.2 Materials -- 2.3 Methods -- 2.4 Statistical Analysis -- 3 Results -- 4 Discussion -- 5 Conclusion -- References -- Preliminary Study on the Identification of Diseases by Electrocardiography Sensors' Data -- 1 Introduction -- 2 Methods -- 2.1 Study Design and Participants -- 2.2 Feature Extraction -- 2.3 Data Classification -- 3 Results -- 4 Discussion and Conclusions -- References. |
Computational Proteomics. |
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Sommario/riassunto |
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This volume constitutes the proceedings of the 10th International Work-Conference on IWBBIO 2023, held in Meloneras, Gran Canaria, Spain, during July 12-14, 2022. The total of 79 papers presented in the proceedings, was carefully reviewed and selected from 209 submissions. The papers cove the latest ideas and realizations in the foundations, theory, models, and applications for interdisciplinary and multidisciplinary research encompassing disciplines of computer science, mathematics, statistics, biology, bioinformatics, and biomedicine. |
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2. |
Record Nr. |
UNINA9910821117303321 |
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Autore |
Atkinson G. B. J. |
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Titolo |
VCP5-DCV : vmware certified professional-data center virtualization on vSphere 5.5 : study guide : exam VCP-550 / / Brian Atkinson |
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Pubbl/distr/stampa |
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Indianapolis, Indiana : , : Sybex, , 2014 |
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©2014 |
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ISBN |
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1-118-76319-X |
1-118-91923-8 |
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Edizione |
[2nd ed.] |
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Descrizione fisica |
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1 online resource (890 p.) |
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Disciplina |
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Soggetti |
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Data recovery (Computer science) |
Virtual computer systems |
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Lingua di pubblicazione |
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Formato |
Materiale a stampa |
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Livello bibliografico |
Monografia |
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Note generali |
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Nota di contenuto |
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Cover; Title Page; Copyright; Contents; Introduction; Assessment Test; Chapter 1 What's New in vSphere 5.5; vSphere ESXi Hypervisor Enhancements; Hot-Pluggable PCIe SSD Devices; Support for Reliable Memory Technology; Enhancements to CPU C-States; Virtual Machine Enhancements; VM Compatibility with VMware ESXi 5.5; Expanded vGPU Support; Graphic Acceleration for Linux Guests; vCenter Server Enhancements; vCenter Single Sign-On; vCenter Server Appliance; vSphere Web Client; vSphere App HA; HA Compatibility with DRS VM-VM Affinity Rules; vSphere Big Data Extensions; Storage Enhancements |
Support for 62TB VMDKMSCS Updates; 16Gb E2E Support; PDL AutoRemove; vSphere Replication Interoperability; vSphere Replication Multi-Point-in-Time (MPIT) Snapshot Retention; VAAI UNMAP Improvements; VMFS Heap Improvements; vSphere Flash Read Cache; Networking Enhancements; Link Aggregation Control Protocol (LACP) Enhancements; Traffic Filtering; Quality of Service Tagging; SR-IOV Enhancements; Enhanced Host-Level Packet Capture; 40Gb NIC Support; VMware Data Protection (VDP) Enhancements; vCenter Operations Manager; Summary |
Chapter 2 Planning, Installing, Configuring, and Upgrading VMware ESXi and vCenter ServerIntroducing VMware ESXi; Identifying ESXi Host Requirements; Performing an Interactive Installation of ESXi; |
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Configuring NTP on an ESXi Host; Configuring DNS and Routing on an ESXi Host; Enabling, Configuring, and Disabling Hyperthreading; Selecting a CPU Power Management Policy; Enabling, Sizing, and Disabling Memory Compression Cache; Licensing an ESXi Host; Introducing vCenter Server; Identifying Available vCenter Server Editions; Identifying vCenter Server and vCenter Server Database Requirements |
Identifying Single Sign-On RequirementsCreating a Database Connection to the vCenter Server Database; Sizing the vCenter Server Database; Installing vCenter Server into a Virtual Machine; Deploying the vCenter Server Appliance; Installing and Configuring the vSphere Client and vSphere Web Client; Describing Single Sign-On Architecture; Differentiating Single-Sign-On Deployment Scenarios; Configuring and Administering Single Sign-On; Managing Single Sign-On Users and Groups; Installing Additional vCenter Server Components; Installing and Removing vSphere Client Plug-Ins |
Enabling and Disabling vSphere Client Plug-InsLicensing vCenter Server; Determining Availability Requirements for a vCenter Server in a Given vSphere Implementation; Planning and Performing Upgrades of vCenter Server and VMware ESXi; Identifying Steps Required to Upgrade a vSphere Implementation; Identifying Upgrade Requirements for ESXi Hosts; Determining Whether an In-Place Upgrade Is Appropriate in a Given Upgrade Scenario; Summary; Exam Essentials; Review Questions; Chapter 3 Securing vCenter Server and ESXi and Identifying vSphere Architecture and Solutions |
Securing vCenter Server and ESXi |
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Sommario/riassunto |
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Prepare for the VCP-DCV Exam Prepare yourself for VMware's challenging VMware Certified Professional-Data Center Virtualization exam, as well as the typical tasks and responsibilities you can expect as a VMware vSphere 5.5-certified professional. This comprehensive book guides you through all topics and objectives you'll need to know for the exam. These include planning, installing, upgrading, and securing vCenter Server and ESXi; configuring networking and storage; performing basic troubleshooting; and more. You'll also gain access to premium online practice and review tools.< |
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