1.

Record Nr.

UNINA9910820441003321

Autore

Bretschneider Franklin <1947->

Titolo

Introduction to electrophysiological methods and instrumentation / / Franklin Bretschneider, Jan R. de Weille

Pubbl/distr/stampa

Amsterdam, : Elsevier/ Academic Press, c2006

ISBN

1-280-64144-4

9786610641444

0-08-046224-3

Edizione

[1st ed.]

Descrizione fisica

1 online resource (267 p.)

Altri autori (Persone)

De WeilleJan R

Disciplina

612.01427

612.813

616.807547

Soggetti

Electrophysiology - Equipment and supplies

Electronics

Lingua di pubblicazione

Inglese

Formato

Materiale a stampa

Livello bibliografico

Monografia

Note generali

Description based upon print version of record.

Nota di bibliografia

Includes bibliographical references and index.

Nota di contenuto

Front cover; Title page; Copyright page; Table of contents; Preface; 1 Electricity; Electrical Quantities; Electric Charge, Current and Potential; Resistance; Capacitance; Magnetism; Self-Inductance; Direct and Alternating Current;  Frequency; Reactance; Current and Voltage Sources; Components, Unwanted Properties; Unwanted Properties, Impedance; Cables; Circuits, Schematics, Kirchoff's Laws; Composition of Similar Components: Attenuators; Practical Voltage Sources and Current Sources; Voltage and Current Measurement; Composition of Unequal Components: Filters; Integration and Differentiation

LC Filters2 Electronics; Active Elements; Vacuum Tubes and Semiconductors; Semiconductor Devices; Diodes and Transistors; Other Semiconductor Types; Amplifiers, Gain, Decibels and Saturation; Gain; Bandwidth; Input and Output Impedances; Maximum Signal Strength, Distortion; Noise, Hum Interference and Grounding; Differential Amplifiers, Block Diagrams; Operational Amplifiers, Feedback; Electronic Filters; Electrophysiological Preamplifiers; Amplifier for Extracellular Recording; Amplifier for Intracellular Recording; Patch-Clamp Amplifier; Two-Electrode Voltage-Clamp Amplifier



Measurement of Membrane Capacitance in Voltage-ClampRecording of Secretory Events; Power Supplies and Signal Sources; Electronic Voltmeters; Electrometers; The Cathode Ray Oscilloscope; LCD Screen Oscilloscopes; Important Properties of Oscilloscopes; Digital Electronics, Logic; A/D and D/A Conversions; Computers; 3 Electrochemistry; Introduction, Properties of Electrolytes; Electrolytes; The Metal/Electrolyte Interface; Capacitance of Polarized Electrodes; Faradaic Processes; Practical Electrodes; Electrochemical Cells, Measuring Electrodes; The Silver/Silver Chloride Electrode

Non-Faradaic ProcessesElectrokinetic Processes; Liquid Junction Potentials; Membrane Potentials; Derivation of the Equilibrium Potential; The Reversal Potential; Ion Selectivity; Electrodes Sensitive to pH and Other Ions; Electrodes: Practical Aspects; The Glass Micropipette; Patch Electrodes; The Semi-Permeable Patch; Ground Electrodes; Volume Conduction: Electric Fields in Electrolyte Solutions; Homogeneous Electric Field; Monopole Field; Dipole Field; 4 Signal Analysis; Introduction; Analysis of Analogue Potentials; Systems Analysis; Convolution; The Laplace Transform

The Fourier TransformOdd and Even Functions; Linearity; Analogue-to-Digital and Digital-to-Analogue Conversions; Signal Windowing; Digital Signal Processing; Signal Averaging; Autocorrelation; Crosscorrelation; The Discrete Fourier Transform; The Detection of Signals of Known Shape; Digital Filters; Fourier Filters and Non-Causal Filters; Non-Linear Systems Analysis; The Formal Method: Wiener Kernel Analysis; The Informal Method: Output Shape Analysis; The Importance of Non-Linearity; Analysis of Action Potential Signals; Population Spike and Gross Activity; Recording from the Skin Surface

The Electrocardiogram

Sommario/riassunto

Introduction to Electrophysiological Methods and Instrumentation covers all topics of interest to electrophysiologists, neuroscientists and neurophysiologists, from the reliable penetration of cells, the behaviour and function of the equipment, to the mathematical tools available for analysing data. It discusses the pros and cons of techniques and methods used in electrophysiology and how to avoid their pitfalls.Particularly in an era where high quality off-the-shelf solutions are readily available, it is important for the electrophysiologist to understand how his or her equipme