1.

Record Nr.

UNINA9910820073903321

Autore

Smith Michael <1946 October 17->

Titolo

Organic synthesis / / Michael B. Smith

Pubbl/distr/stampa

[Boston], : Academic Press, an imprint of Elsevier, [2011]

ISBN

1-280-58131-X

9786613611093

0-12-415884-6

Edizione

[3rd ed.]

Descrizione fisica

1 online resource (1536 p.)

Disciplina

547/.2

Soggetti

Organic compounds - Synthesis

Lingua di pubblicazione

Inglese

Formato

Materiale a stampa

Livello bibliografico

Monografia

Note generali

Description based upon print version of record.

Nota di bibliografia

Includes bibliographical references and indexes.

Nota di contenuto

Front Cover; Organic Synthesis; Copyright Page; About the Author; Table of Contents; Preface to the 3rd edition; Preface to the 1st edition. Why I wrote this book!; Common Abbreviations; Chapter 1: Retrosynthesis, Stereochemistry, and Conformations; 1.1. Introduction; 1.2. The Disconnection Protocol; 1.3. Bond Proximity and Implications for Chemical Reactions; 1.4. Stereochemistry; 1.5. Conformations; 1.6. Conclusion; Homework; Chapter 2: Acids, Bases and Functional Group Exchange Reactions; 2.1. Introduction; 2.2. Brønsted-Lowry Acids and Bases; 2.3. Lewis Acids

4.6. Borane, Aluminum Hydride, and Derivatives4.7. Stereoselectivity in Reductions; 4.8. Catalytic Hydrogenation; 4.9. Dissolving Metal Reductions; 4.10. Nonmetallic Reducing Agents; 4.11. Conclusion; Homework; Chapter 5 : Hydroboration; 5.1. Introduction; 5.2. Preparation of Alkyl and Alkenyl Boranes; 5.3. Synthetic Transformations; 5.4. Formation of Oxygen-Containing Functional Groups; 5.5. Amines and Sulfides via Hydroboration; 5.6. Conclusion; Homework; Chapter 6 : Stereocontrol and Ring Formation; 6.1. Introduction; 6.2. Stereocontrol in AcyclIc Systems

8.5. OrganoLithium Reagents (C-Li)

Sommario/riassunto

A reactions oriented course is a staple of most graduate organic programs, and synthesis is taught either as a part of that course or as a special topic. Ideally, the incoming student is an organic major, who



has a good working knowledge of basic reactions, stereochemistry and conformational principles. In fact, however, many (often most) of the students in a first year graduate level organic course have deficiencies in their undergraduate work, are not organic majors and are not synthetically inclined.   To save students much time catching up this text provides a reliable and readily