1.

Record Nr.

UNINA9910819846903321

Autore

Brushart Thomas M

Titolo

Nerve repair : the scientific basis / / Thomas M. Brushart

Pubbl/distr/stampa

New York, : Oxford University Press, 2011

ISBN

0-19-996516-1

0-19-972160-2

Edizione

[1st ed.]

Descrizione fisica

1 online resource (476 p.)

Disciplina

617.4/81044

Soggetti

Nervous system - Wounds and injuries

Nervous system - Regeneration

Nerves, Peripheral - Surgery

Lingua di pubblicazione

Inglese

Formato

Materiale a stampa

Livello bibliografico

Monografia

Note generali

Description based upon print version of record.

Nota di bibliografia

Includes bibliographical references.

Nota di contenuto

Peripheral nerve anatomy and function -- Touch -- Motion -- Determining clinical outcomes -- Clinical nerve repair and grafting -- Determining experimental outcome -- Outcomes of experimental nerve repair and grafting -- The nerve gap : beyond autograft -- Nerve regeneration -- Specificity in nerve regeneration -- Systems of organization after nerve repair or transfer -- Treatment strategies.

Sommario/riassunto

Peripheral nerves are biologic wires that convey the desire for motion from brain to muscle, and the experience of touch from skin to brain. When a nerve is cut, the individual fibers, or axons, must regenerate from the site of injury to reconnect with their skin and muscle targets. Nerve regeneration is a process of bewildering complexity that requires the coordinated action of multiple biologic systems. Gene expression within the neuron is altered to support axon growth, regenerating axons must cross the complex environment of the nerve injury and enter pathways that lead to functionally app