|
|
|
|
|
|
|
|
1. |
Record Nr. |
UNINA9910819578803321 |
|
|
Titolo |
Hormones and transport systems / / edited by Gerald Litwack ; contributors, Yasaman Aghazadeh [and thirty-eight others] |
|
|
|
|
|
|
|
Pubbl/distr/stampa |
|
|
Amsterdam, [Netherlands] : , : Academic Press, , 2015 |
|
©2015 |
|
|
|
|
|
|
|
|
|
ISBN |
|
0-12-803008-9 |
0-12-803028-3 |
|
|
|
|
|
|
|
|
Edizione |
[First edition.] |
|
|
|
|
|
Descrizione fisica |
|
1 online resource (584 p.) |
|
|
|
|
|
|
Collana |
|
Vitamins and Hormones, , 0083-6729 ; ; Volume ninety eight |
|
|
|
|
|
|
Disciplina |
|
|
|
|
|
|
Soggetti |
|
|
|
|
|
|
Lingua di pubblicazione |
|
|
|
|
|
|
Formato |
Materiale a stampa |
|
|
|
|
|
Livello bibliografico |
Monografia |
|
|
|
|
|
Note generali |
|
Description based upon print version of record. |
|
|
|
|
|
|
Nota di bibliografia |
|
Includes bibliographical references at the end of each chapters and index. |
|
|
|
|
|
|
|
|
Nota di contenuto |
|
Front Cover; Hormones and Transport Systems; Copyright; Former Editors; Contents; Contributors; Preface; Chapter One: Dietary I- Absorption: Expression and Regulation of the Na+/I- Symporter in the Intestine; 1. The Importance of Iodide in Human Health; 2. The Na+/I- Symporter; 2.1. Molecular identification of NIS; 2.2. NIS-mediated transport: Substrates and stoichiometry; 2.3. The role of physiological Na+ concentrations in NIS affinity for I-; 3. NIS Expression Beyond the Thyroid; 4. Targeting of NIS to the Plasma Membrane; 5. Hormonal Regulation of NIS Expression; 6. Dietary I- Absorption |
7. Regulation of Intestinal NIS Expression8. Conclusions and Future Directions; Acknowledgments; References; Chapter Two: Apical Iodide Efflux in Thyroid; 1. Introduction; 2. Iodide and Thyroid Hormone Synthesis; 2.1. Thyroid organization; 2.2. Thyroid hormone synthesis; 3. Vectorial Transport Processes in Epithelia and Thyroid I- Accumulation; 3.1. Brief overview of basic epithelial transport processes; 3.2. Basolateral iodide uptake; 3.3. Apical iodide release; 4. Chloride Transport Proteins and Luminal I- Translocation; 4.1. SLC26A4 (Pendrin); 4.1.1. SLC26A4, HCO3-, luminal pH |
4.2. Cystic fibrosis transmembrane conductance regulator4.2.1. CFTR and SLC26A4 interplay; 4.3. SLC5A8, a sodium-monocarboxylate transporter (hAIT; SLC5A8; SMCT1); 4.4. TMEM16A (anoctamin 1); 5. |
|
|
|
|