Drug concentrations in neuropsychiatry

• Record Nr.: UNINA9910818860903321
• Pubbl/distr/stampa: Amsterdam ; ; New York, : Excerpta Medica; New York, N.Y., : Elsevier/North-Holland, 1980
• ISBN: 9786613694232; 9780470720578; 0470720573; 9781280783845; 1280783842; 9780470718254; 0470718250
• Edizione: [1st ed.]
• Descrizione fisica: 1 online resource (192 p.)
• Collana: Ciba Foundation symposium (new series) ; ; 74
• Disciplina: 616.89/18
• Soggetti: Neuropsychopharmacology; Psychotropic drugs
• Lingua di pubblicazione: Inglese
• Formato: Materiale a stampa
• Livello bibliografico: Monografia
• Note generali: "Symposium on Drug Concentrations in Neuropsychiatry, held at the Ciba Foundation, London, 4th-5th July 1979"--Participants page.
• Nota di bibliografia: Includes bibliographical references and indexes.
• Nota di contenuto: Intro -- Drug Concentrations in Neuropsychiatry -- Contents -- Introduction: The rational use of plasma drug levels in clinical medicine -- Discussion -- Principles of pharmacokinetics -- Discussion -- Methodological pitfalls: the influence of experimental design on results -- Discussion -- Interpretation of drug levels: relevance of plasma binding -- Discussion -- Quality control of drug assays -- Discussion -- Lithium concentrations and clinical responses -- Discussion -- Blood levels of flupenthixol in patients with acute and chronic schizophrenia -- Discussion -- Clinical significance of monitoring plasma levels of psychotropic drugs -- Discussion -- Benzodiazepines: some aspects of their clinical pharmacology -- Discussion -- Adrenergic and serotonergic mechanisms in depression and their response to amitriptyline -- Discussion -- The role of plasma level monitoring of tricyclic antidepressant drugs as an aid to treatment -- Discussion -- Clinical application of the monitoring of anticonvulsant ; drug levels -- Discussion -- The logistics of drug monitoring -- Discussion -- Alternative approaches -- Discussion -- GENERAL DISCUSSION -- Statistics and experimental design -- Further research on drug levels -- A guide for the doctor -- Concluding remarks -- Appendix Monitoring plasma concentrations of psychotropic drugs as an aid to treatment -- Index of contributors -- Subject index.
• Sommario/riassunto: The Novartis Foundation Series is a popular collection of the proceedings from Novartis Foundation Symposia, in which groups of leading scientists from a range of topics across biology, chemistry and medicine assembled to present papers and discuss results. The Novartis Foundation, originally known as the Ciba Foundation, is well known to scientists and clinicians around the world.