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Record Nr. |
UNINA9910818372403321 |
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Autore |
Torrents Eduard |
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Titolo |
The ribonucleotide reductase family : genetics and genomics / / Eduard Torrents, Margareta Sahlin and Britt-Marie Sjoberg |
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Pubbl/distr/stampa |
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New York, : Nova Biomedical Books, c2009 |
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ISBN |
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Edizione |
[1st ed.] |
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Descrizione fisica |
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1 online resource (109 p.) |
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Collana |
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Novinka The ribonucleotide reductase family |
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Altri autori (Persone) |
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SahlinMargareta |
SjobergBritt-Marie |
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Disciplina |
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Soggetti |
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Oxidoreductases |
Enzymes |
Genetics |
Genomics |
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Lingua di pubblicazione |
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Formato |
Materiale a stampa |
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Livello bibliografico |
Monografia |
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Note generali |
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Description based upon print version of record. |
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Nota di bibliografia |
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Includes bibliographical references (p. [65]-87) and index. |
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Nota di contenuto |
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Intro -- THE RIBONUCLEOTIDEREDUCTASE FAMILY:GENETICS AND GENOMICS -- Contents -- Preface -- Introduction -- RNR Classification and Occurrence -- Class I RNRs -- Class II RNRs -- Class III RNRs -- RNR distribution as seen in RNRdb -Ribonucleotide Reductase Database -- Atypical and Unconventional RNRs -- RNR Diversification -- Modularity Hypothesis for RNR ClassDiversificatio -- Regulation of RNRs -- Archaea -- Eubacteria -- Mutational Studies in RNRs -- RNR as an Antiproliferative Targetfor Disease Control -- Substrate Analogues -- Radical Scavengers Attacking the TyrosylRadical -- Iron Chelators -- Peptidomimetics Corresponding to the CTerminusof NrdB -- Manipulating the Expression of RNR -- Other Potential Inhibitors and AllostericNucleotide Analogues -- Future Antiproliferative Regimes -- Acknowledgments -- References -- Index. |
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