1.

Record Nr.

UNINA9910817929103321

Titolo

Protein kinase CK2 [[electronic resource] /] / edited by Lorenzo A. Pinna

Pubbl/distr/stampa

Ames, Iowa, : Wiley-Blackwell, : IUBMB, 2013

ISBN

1-118-48234-4

1-118-48249-2

1-283-70015-8

1-118-48238-7

Edizione

[1st ed.]

Descrizione fisica

1 online resource (482 p.)

Collana

Wiley-IUBMB series on biochemistry and molecular biology

Altri autori (Persone)

PinnaLorenzo A

Disciplina

612/.015756

Soggetti

Protein kinase CK2

Lingua di pubblicazione

Inglese

Formato

Materiale a stampa

Livello bibliografico

Monografia

Note generali

Description based upon print version of record.

Nota di bibliografia

Includes bibliographical references and index.

Nota di contenuto

pt. 1. Molecular and structural aspects -- pt. 2. Functional aspects -- pt. 3. CK2 and Neoplasia.

Sommario/riassunto

The importance of CK2 in cancer and other diseases has generated a significant amount of literature on the protein, and an international community of CK2 researchers. The International Union of Biochemistry and Molecular Biology (IUMBMB) sponsors periodic international conferences on CK2, making the protein a natural topic for a Wiley-IUBMB publication. Protein Kinase CK2 will deal with structural aspects underlying the constitutive activity of CK2, its specific susceptibility to pharmacological inhibition and its extraordinary pleiotropy. In the second part the fundamental role of CK