Reproductive endocrinology for the MRCOG and beyond / / edited by Adam Balen

• Record Nr.: UNINA9910817721403321
• Pubbl/distr/stampa: London : , : RCOG Press, , 2007
• ISBN: 1-107-71091-X; 1-107-71433-8; 9786611894320; 1-281-89432-X; 1-904752-72-1; 1-139-69692-0
• Edizione: [Second edition.]
• Descrizione fisica: 1 online resource (xii, 214 pages) : digital, PDF file(s)
• Collana: MRCOG and beyond series
• Disciplina: 618.1
• Soggetti: Human reproduction - Endocrine aspects
• Lingua di pubblicazione: Inglese
• Formato: Materiale a stampa
• Livello bibliografico: Monografia
• Note generali: Title from publisher's bibliographic system (viewed on 05 Oct 2015).
• Nota di bibliografia: Includes bibliographical references and index.
• Nota di contenuto: Cover -- Published titles in the MRCOG and Beyond series -- Contents -- Acknowledgments -- Preface to the first edition -- Preface to the second edition -- Abbreviations -- 1. Sexual differentiation: intersex disorders -- Development of the internal and external genitalia -- Origin of the ovaries and oocytes -- Origin of the uterus and fallopian tubes -- Development of external genitalia -- NEWBORN APPEARANCE -- Disorders of development of internal andexternal genitalia -- MULLERIAN DUCT ABNORMALITIES -- CONGENITAL ABSENCE OF THE VAGINA -- FUSION ABNORMALITIES OF THE VAGINA -- MULLERIAN/UTERINE ANOMALIES -- Androgen insensitivity syndrome -- 5-ALPHA REDUCTASE DEFICIENCY -- Congenital adrenal hyperplasia -- Cloacal anomalies -- Management of intersex conditions -- Reference -- 2. Adrenal disorders -- The adrenal medulla -- EFFECTS OF ADRENALINE AND NORADRENALINE -- PHAEOCHROMOCYTOMA -- The adrenal cortex -- HYPERFUNCTION OF THE ADRENAL CORTEX -- 3. Normal puberty and adolescence -- Pubertal development -- ONSET OF PUBERTAL DEVELOPMENT -- References -- 4. Abnormal puberty -- Precocious puberty -- TRUE PRECOCIOUS PUBERTY -- PREMATURE ; THELARCHE -- THELARCHE VARIANT -- PREMATURE ADRENARCHE -- CONGENITAL ADRENAL HYPERPLASIA -- PERIPHERAL TUMOURS -- MANAGEMENT OF PRECOCIOUS PUBERTY -- CONSTITUTIONAL DELAY OF GROWTH AND PUBERTY -- TURNER SYNDROME -- POLYGLANDULAR AUTOIMMUNE SYNDROMES -- CONGENITAL HYPOGONADOTROPHIC HYPOGONADISM -- MANAGEMENT OF DELAYED PUBERTY -- Delayed puberty -- CONSTITUTIONAL DELAY OF GROWTH AND PUBERTY -- TURNER SYNDROME -- POLYGLANDULAR AUTOIMMUNE SYNDROMES -- CONGENITAL HYPOGONADOTROPHIC HYPOGONADISM -- MANAGEMENT OF DELAYED PUBERTY -- Reference -- 5. The menstrual cycle -- Ovulation during the perimenopausal transition -- References -- 6. Disorders of menstruation -- Normal menstruation -- VARIATION IN MENSTRUAL BLOOD LOSS.; VARIATION IN CYCLE LENGTH AND DURATION OF MENSTRUATION -- The abnormal menstrual cycle -- MENORRHAGIA -- ASSESSMENT OF MENSTRUAL BLOOD LOSS -- CAUSES OF MENORRHAGIA -- DIAGNOSIS OF MENORRHAGIA -- Methods of endometrial assessment -- ENDOMETRIAL BIOPSY -- HYSTEROSCOPY -- TRANSVAGINAL ULTRASOUND -- Initial management of menorrhagia in primary care -- Medical treatment of menorrhagia -- NON-HORMONAL TREATMENTS -- HORMONAL TREATMENTS -- TREATMENT FAILURES -- Surgical treatment of menorrhagia -- HYSTERECTOMY -- OVARIES AND HYSTERECTOMY -- ENDOMETRIAL ABLATIVE TECHNIQUES -- COMPARISON OF ENDOMETRIAL ABLATIVE TECHNIQUES WITH HYSTERECTOMY -- Counselling in menorrhagia -- The ideal management of menorrhagia -- Fibroids -- MANAGEMENT -- Dysmenorrhoea -- PRIMARY DYSMENORRHOEA -- SECONDARY DYSMENORRHOEA -- TREATMENT -- ASSESSMENT -- References -- 7. Amenorrhoea -- Primary amenorrhoea -- Secondary amenorrhoea -- Examination and investigation of amenorrhoea -- Causes of amenorrhoea -- GENITAL TRACT ABNORMALITIES -- SYSTEMIC DISORDERS CAUSING SECONDARY AMENORRHOEA -- WEIGHT-RELATED AMENORRHOEA -- LEPTIN -- PSYCHOLOGICAL STRESS -- EXERCISE-RELATED AMENORRHOEA -- HYPOTHALAMIC CAUSES OF SECONDARY AMENORRHOEA -- PITUITARY CAUSES OF SECONDARY AMENORRHOEA -- IATROGENIC CAUSES OF AMENORRHOEA -- 8. Polycystic ovary syndrome -- Pathogenesis -- GENETICS OF POLYCYSTIC OVARY SYNDROME -- HETEROGENEITY OF POLYCYSTIC OVARY SYNDROME -- Management of polycystic ovary syndrome -- OBESITY -- MENSTRUAL IRREGULARITY -- INFERTILITY -- HYPERANDROGENISM AND HIRSUTISM -- References -- 9. Health consequences of polycystic ovary syndrome -- Insulin resistance -- Insulin resistance in polycystic ovary syndrome -- Other risk factors for ischaemic heart disease in women with polycystic ovary syndrome -- CENTRAL OBESITY -- IMPAIRED GLUCOSE TOLERANCE AND DIABETES -- HYPERTENSION -- DYSLIPIDAEMIA.; HYPERHOMOCYSTEINAEMIA -- Polycystic ovary syndrome in younger women -- Long-term follow-up in polycystic ovary syndrome -- Therapeutic options -- Polycystic ovary syndrome and cancer -- ENDOMETRIAL CANCER -- BREAST CANCER -- OVARIAN CANCER -- References -- 10. Anovulatory infertility andovulation induction -- Pituitary and hypothalamic causes of anovulation -- HYPOGONADOTROPHIC HYPOGONADISM -- WEIGHT-RELATED AMENORRHOEA -- Polycystic ovary syndrome (see also Chapter 8) -- LIFESTYLE AND WEIGHT LOSS IN POLYCYSTIC OVARY SYNDROME -- CLOMIFENE CITRATE THERAPY -- AROMATASE INHIBITORS -- GONADOTROPHIN THERAPY -- SURGICAL OVULATION INDUCTION -- THE ROLE OF METFORMIN AND OTHER INSULIN SENSITISERS -- IVF IN WOMEN WITH POLYCYSTIC OVARIES -- IN VITRO MATURATION OF ; OOCYTES -- Risks of ovulation induction -- Ovarian hyperstimulation syndrome -- MANAGEMENT OF OVARIAN HYPERSTIMULATION SYNDROME -- Summary -- References -- 11. Lactation and lactational amenorrhoea -- Initiation of lactation -- Maintenance of lactation and milk letdown -- Endocrine effects of lactation -- AMENORRHOEA -- HYPOESTROGENAEMIA -- SOCIAL EFFECTS -- Metabolic effects of lactation -- DIET -- WEIGHT CHANGE -- CONTROL OF LACTATION -- Lactation and contraception -- NATURAL CONTRACEPTION -- ARTIFICIAL CONTRACEPTION -- References -- 12. Hyperprolactinaemia -- MEDICAL MANAGEMENT -- SURGICAL MANAGEMENT -- EFFECT ON PREGNANCY -- Reference -- 13. Thyroid disease -- Scientific background -- Thyroid function -- CLINICAL EXAMINATION OF THE THYROID GLAND -- Classification and diagnosis (Table 13.2) -- SIMPLE NON-TOXIC GOITRE -- HYPOTHYROIDISM -- HYPERTHYROIDISM -- 14. Diabetes -- Definition -- Treatment and control -- Relevance to fertility -- Relevance to pregnancy -- Management of diabetes in pregnancy -- Managing the complications of diabetes inpregnancy.; Managing the complications of pregnancy in women with diabetes -- Type 2 diabetes, hyperinsulinaemia and insulin resistance -- References -- 15. Lipid metabolism and lipoprotein transport -- Transport of dietary fat -- HEPATIC LIPID METABOLISM -- ENDOGENOUS LIPID TRANSPORT -- HIGH-DENSITY LIPOPROTEINS AND REVERSE CHOLESTEROL TRANSPORT -- The effect of menopause on plasma lipoproteins -- References -- 16. Premature ovarian failure -- The control of ovarian ageing -- Definition and diagnosis -- Causation -- GENETIC CAUSES -- FAMILIAL FACTORS -- AUTOIMMUNE CAUSES -- Management -- OOCYTE DONATION -- CRYOPRESERVATION OF OVARIAN TISSUE -- References -- 17. Calcium metabolism and its disorders -- Calcium and bone homeostasis -- Parathyroid hormone and calcium -- Renal disease and calcium -- Osteoporosis and calcium -- References -- Appendix: Endocrine normal ranges -- Further reading -- Index.
• Sommario/riassunto: Understanding endocrinology is central to understanding the key processes that affect normal reproductive function, while an understanding of normal endocrinology and the pathophysiology of endocrine disorders is important when dealing with reproductive disorders. This book provides a comprehensive background for all gynaecologists, covering: sexual differentiation and intersex disorders; adrenal disorders; normal puberty and adolescence; abnormal puberty; the menstrual cycle; disorders of menstruation; amenorrhoea; polycystic ovary syndrome; anovulatory fertility and ovulation induction; lactation and lactational amenorrhoea; hyperprolactinaemia; thyroid disease; diabetes; lipid metabolism and lipoprotein transport; premature ovarian failure; and calcium metabolism and its disorders. The book is primarily designed to provide a comprehensive summary for candidates preparing for the Part 2 MRCOG examination, and as such covers the RCOG curriculum for reproductive endocrinology. It is also a valuable guide for all healthcare professionals working in the field, including trainees, consultants and any health professional coming into contact with women.