1.

Record Nr.

UNINA9910817637403321

Titolo

Pancreatic cancer, cystic neoplasms and endocrine tumors : diagnosis and management / / edited by Hans G. Beger [and four others] ; cover design by Sarah Dickinson ; contributors, Hana Algül [and one hundred nineteen others]

Pubbl/distr/stampa

Chichester, England : , : Wiley Blackwell, , 2015

©2015

ISBN

1-118-30783-6

1-118-30781-X

1-118-30784-4

Descrizione fisica

1 online resource (459 p.)

Disciplina

616.99/437

Soggetti

Pancreas - Cancer

Pancreas - Cancer - Diagnosis

Neuroendocrine tumors

Lingua di pubblicazione

Inglese

Formato

Materiale a stampa

Livello bibliografico

Monografia

Note generali

Includes index.

Nota di bibliografia

Includes bibliographical references at the end of each chapters and index.

Nota di contenuto

Cover; Title page; Copyright page; Contents; Contributors; Preface; Abbreviations; PART I: Ductal adenocarcinoma of the pancreas; CHAPTER 1: Histologic classification and tumor staging of pancreatic cancer; Histologic classification of pancreatic ductal neoplasms; Atypical epithelium and carcinoma in situ; Invasive ductal carcinomas; Tumor staging; References; CHAPTER 2: What we know about carcinogenesis of ductal adenocarcinoma of the pancreas; Pancreatic cancer cell; Pancreatic cancer stem cells; Tumor stroma cells; References; CHAPTER 3: Familial cancer of the pancreas; Introduction

DefinitionPhenotype; Pathology; Genetic background; Genetic counselling and testing; Screening; Candidates and targets for screening; Current screening modalities; Timing and frequency of screening; Success of screening programs; Management of suspicious lesions; Psychooncological aspects of PDAC screening; Conclusion; References; CHAPTER 4: Clinical, laboratory, and radiologic



presentation of pancreatic cancer; Clinical presentation; Laboratory investigations; Radiologic investigations; References; CHAPTER 5: Standards of oncologic pancreatic surgery; Overview; Preoperative considerations

Preoperative biliary drainageImaging; Staging laparoscopy; Goals of surgical treatment; Operative techniques; Pylorus-preserving pancreatoduodenectomy; Classic "Whipple"; Distal pancreatectomy with en bloc splenectomy; Complete R0 versus R1 resection; Standard (D1) versus extended (D2) lymphadenectomy; Minimally invasive pancreatic resections; Robotic and laparoscopic pancreatoduodenectomy; Robotic and laparoscopic distal pancreatectomies; Postoperative course, complications, and adjuvant treatment; Postoperative recovery; Postoperative complications and management; Conclusion; References

CHAPTER 6: Extended resection for pancreatic cancer: risks and benefitsIntroduction; History of portal vein resection; Diagnosis of cancer invasion of the portal vein; Indications for portal vein resection; Isolated pancreatoduodenectomy with portal vein resection; Mesenteric approach; Catheter bypass of the portal vein; Portal vein resection and reconstruction; Postoperative mortality at Nagoya University Hospital; Long-term survival following portal vein resection; References; CHAPTER 7: Risk/benefit of total pancreatectomy for pancreatic cancer: are there indications?; Historical notes

Benefits versus disadvantagesPancreatic malabsorption; Pancreatic diabetes; New indications; Modified surgical techniques; Pylorus-preserving total pancreatectomy; Total pancreatectomy with preservation of stomach and spleen; Re-resection for recurrent cancer; Results of total pancreatectomy; Rescue pancreatectomy; Isolated neck margin positive pancreatic adenocarcinoma; In children; Total pancreatectomy with islet transplantation; Conclusion; References; CHAPTER 8: Is there a benefit from additional arterial resection of ductal cancer of the pancreas?; Introduction

Arterial resection in pancreatectomy following preoperative chemotherapy or chemoradiotherapy

Sommario/riassunto

Pancreatic Cancer, Cystic Neoplasms and Endocrine Tumors: Diagnosis and Management is a modern, expertly crafted and clinically focused guide to the diagnosis, management and best-practice care of patients suffering from pancreatic cancer, cystic neoplasms and endocrine tumours.   Packed with outstanding figures and with reference to the leading society guidelines, its main focus is on the many endoscopic and radiologic diagnostic techniques, medical and surgical management of both full-blown cancer and other tumors, and the risks of each form of treatment.  Also covered in detail are issues