|
|
|
|
|
|
|
|
1. |
Record Nr. |
UNINA9910814940003321 |
|
|
Autore |
Miteva Maria A |
|
|
Titolo |
In silico lead discovery / / by Maria A. Miteva |
|
|
|
|
|
Pubbl/distr/stampa |
|
|
[Saif Zone, Sharjah, United Arab Emirates], : Bentham Science Publishers Ltd., [2011] |
|
|
|
|
|
|
|
|
|
ISBN |
|
|
|
|
|
|
Edizione |
[1st ed.] |
|
|
|
|
|
Descrizione fisica |
|
1 online resource (201 p.) |
|
|
|
|
|
|
Disciplina |
|
|
|
|
|
|
Soggetti |
|
Drug development |
Drug development - Computer simulation |
|
|
|
|
|
|
|
|
Lingua di pubblicazione |
|
|
|
|
|
|
Formato |
Materiale a stampa |
|
|
|
|
|
Livello bibliografico |
Monografia |
|
|
|
|
|
Note generali |
|
Description based upon print version of record. |
|
|
|
|
|
|
Nota di bibliografia |
|
Includes bibliographical references and index. |
|
|
|
|
|
|
Nota di contenuto |
|
01 Title.pdf; 02 Cover Page; 03 eBooks End User License Agreement-Website; 04 Content; 05 Foreword_Grigirov; 06 Preface_Miteva; 07 Contributors_Proposal_forEbook-MariaMiteva; 08 Chapter 1 Lagorce_et al_revised 2; 09 Chapter 2 Sperandio_et al_revised 2; 10 Chapter 3 Guyon_Tuffery_corrected 2; 11 Chapter 4 Todorov_corrected 2; 12 Chapter 5 Alexov_revised 2; 13 Chapter 6 Miteva_revised 2; 14 Chapter 7 Roche-revised 2; 15 Chapter 8 Pajeva_Wiese_revised 2; 16 Chapter 9 Moro_revised 2; 17 Chapter 10 Lee; 18 Index |
|
|
|
|
|
|
|
|
Sommario/riassunto |
|
Computer-aided drug design and in silico screening have contributed to the discovery of several compounds that have either reached the market or entered clinical trials. In silico Lead Discovery is a compilation of the efforts of several experts on bioinformatics and drug design in developing the latest advances of in silico approaches for lead discovery. It contains an overview of structure-based, ligand-based methods and current fragment-based methods as well as examples for successful applications of such methods in discovering new hit/lead molecules for important therapeutic targets. Treat |
|
|
|
|
|
|
|