1.

Record Nr.

UNINA9910814499003321

Titolo

Evidence synthesis for decision making in healthcare / / Nicky J. Welton ... [et al.]

Pubbl/distr/stampa

Chichester, West Sussex, : John Wiley & Sons, 2012

ISBN

9786613620774

9781280590948

1280590947

9781118305409

111830540X

9781119942986

1119942985

9781119942979

1119942977

Edizione

[1st ed.]

Descrizione fisica

1 online resource (296 p.)

Collana

Statistics in practice

Altri autori (Persone)

WeltonNicky J

Disciplina

362.1068/4

Soggetti

Evidence-based medicine - Statistical methods

Lingua di pubblicazione

Inglese

Formato

Materiale a stampa

Livello bibliografico

Monografia

Note generali

Description based upon print version of record.

Nota di bibliografia

Includes bibliographical references and index.

Nota di contenuto

Introduction -- Bayesian methods and winBUGS -- Introduction to decision models -- Meta-analysis using Bayesian methods -- Exploring between study heterogeneity -- Model critique and evidence consistency in random effects meta-analysis -- Evidence synthesis in a decision modelling framework -- Multi-parameter evidence synthesis in epidemiological models -- Mixed treatment comparisons -- Markov models -- Generalised evidence synthesis -- Expected value of information for research prioritisation and study design.

Sommario/riassunto

In the evaluation of healthcare, rigorous methods of quantitative assessment are necessary to establish interventions that are both effective and cost-effective. Usually a single study will not fully address these issues and it is desirable to synthesize evidence from multiple sources. This book aims to provide a practical guide to evidence synthesis for the purpose of decision making, starting with a simple



single parameter model, where all studies estimate the same quantity (pairwise meta-analysis) and progressing to more complex multi-parameter structures (including meta-regression, mixe