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Record Nr. |
UNINA9910813997903321 |
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Titolo |
Basic pharmacokinetics and pharmacodynamics : an integrated textbook and computer simulations / / edited by Sara E. Rosenbaum |
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Pubbl/distr/stampa |
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Hoboken, New Jersey : , : John Wiley & Sons, Incorporated, , [2017] |
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2017 |
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ISBN |
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Edizione |
[Second edition.] |
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Descrizione fisica |
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1 online resource (757 pages) : illustrations |
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Disciplina |
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Soggetti |
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Computer simulation |
Pharmacokinetics |
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Lingua di pubblicazione |
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Formato |
Materiale a stampa |
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Livello bibliografico |
Monografia |
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Nota di bibliografia |
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Includes bibliographical references and index. |
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Nota di contenuto |
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Introduction to pharmacokinetics and pharmacodynamics -- Passage of drugs through membranes -- Drug administration and drug absorption / Steven Sutton -- Drug distribution -- Drug elimination and clearance -- Compartmental models in pharmacokinetics -- Pharmacokinetics of an intravenous bolus injection in a one-compartment model -- Pharmacokinetics of an intravenous bolus injection in a two-compartment model -- Pharmacokinetics of extravascular drug administration / Steven Sutton -- Introduction to noncompartmental analysis -- Pharmacokinetics of intravenous infusion in a one-compartment model -- Multiple intravenous bolus injections in the one-compartment model -- Multiple intermittent infusions -- Multiple oral doses -- Nonlinear pharmacokinetics -- Introduction to pharmacogenetics -- Models used to predict drug-drug interactions for orally administered drugs -- Introduction to physiologically based pharmacokinetic modeling -- Introduction to pharmacodynamic models and integrated pharmacokinetic--pharmacodynamic models / Diane Mould and Paul Hutson -- Semi-mechanistic pharmacokinetic--pharmacodynamic model / Diane Mould and Paul Hutson. |
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