1.

Record Nr.

UNINA9910813127403321

Titolo

Clinical trials in older people / / edited by Antonio Cherubini [and five others] ; contributors Heather Allore [and thirty five others]

Pubbl/distr/stampa

Chichester, England : , : Wiley Blackwell, , 2015

©2015

ISBN

1-118-32348-3

1-118-32343-2

1-118-32347-5

Descrizione fisica

1 online resource (308 p.)

Disciplina

610.72/40846

Soggetti

Clinical trials

Gerontology - Research

Lingua di pubblicazione

Inglese

Formato

Materiale a stampa

Livello bibliografico

Monografia

Note generali

Description based upon print version of record.

Nota di bibliografia

Includes bibliographical references at the end of each chapters and index.

Nota di contenuto

The exclusion of older subjects from clinical trials : the predict study / Antonio Cherubini, Peter Crome -- Clinical trials in older adults : a point of view from the industry / Susanna Del Signore, Philippe Guillet -- Ethical issues in clinical trials involving older subjects : the right to participate in clinical trials and have access to care; the protection of vulnerable subjects and the issue of informed consent / Emmanuel Hirsch, Paul-Loup Weil-Dubuc -- Mastering the design of clinical trials for older persons : the tension between external validity and feasibility / Luigi Ferrucci, Stephanie Studenski -- Pharmacokinetic and pharmacodynamic studies in older adults / Arduino A Mangoni, Paul AF Jansen, Stephen H.D. Jackson -- The role of comprehensive geriatric assessment of older adults in clinical studies / Graziano Onder, Agnese Collamati, Andrea Poscia, Roberto Bernabei -- Statistical issues in designing and interpreting clinical trials in older adults / Heather Allore, Mark A. Espeland, Michael E. Miller -- Challenges in implementing large-scale clinical trials in moderately functioning older adults / Stephen D. Anton, Sandrine Sourdet, Marco Pahor, & Todd Manini -- Clinical trials in Alzheimer's disease / Julien Delrieu , Bruno Vellas -- Clinical trials in late-life mood disorders / Lucio Ghio, Werner



Natta, Marco Vaggi, Luigi Ferrannini -- Clinical trials for conditions of low muscle mass and strength / Stephanie Studenski, Rosaly Correa-de-Araujo and Luigi Ferrucci -- Clinical trials of cancer treatment in the elderly / Lodovico Balducci, Iordanis Gravanis, Francesco Pignatti -- Clinical trials in nursing homes : challenges and practical solutions / Sandra Simmons, Barbara Resnik, John Schnelle, Joe Ouslander.