1.

Record Nr.

UNINA9910812984803321

Titolo

The functions, disease-related dysfunctions, and therapeutic targeting of neuronal mitochondria / / edited by Valentin K. Gribkoff, Elizabeth A. Jonas, J. Marie Hardwick ; contributors, Kambiz N. Alavian [and forty six others]

Pubbl/distr/stampa

[Place of publication not identified] : , : Wiley, , 2015

©2015

ISBN

1-119-01710-6

1-119-01712-2

1-119-01672-X

Descrizione fisica

1 online resource (526 p.)

Collana

Wiley Series on Neuropharmacology

Disciplina

572.869

Soggetti

Mitochondrial pathology

Mitochondria - Formation

Nervous system - Diseases - Treatment

Lingua di pubblicazione

Inglese

Formato

Materiale a stampa

Livello bibliografico

Monografia

Note generali

Description based upon print version of record.

Nota di bibliografia

Includes bibliographical references at the end of each chapters and index.

Nota di contenuto

Mitochondrial permeability transition : look from a different angle / N. Brustovetsky -- The mitochondrial permeability transition pore, the c-subunit of the F1Fo ATP synthase, cellular development and synaptic efficiency / E.A. Jonas, G.A. Porter, Jr., G. Beutner, N. Mnatsakanyan and K.A. Alavian -- Mitochondrial channels in neurodegeneration / P.M. Peixoto, K.W. Kinnally and Evgeny Pavlov -- Mitochondrial Ca2+ transport in the control of neuronal functions : molecular and cellular mechanisms / Y.M. Usachev -- AMP-activated protein kinase (AMPK) as a cellular energy sensor and therapeutic target for neuroprotection / P. Weisova, S. Pfeiffer and J.H.M. Prehn -- HDAC6 : a molecule with multiple functions in neurodegenerative diseases / Y. Yan and R. Jiao -- Neuronal mitochondrial transport / A.L. Knight, Y. Chen, T. Sun and Z.-H. Sheng -- Mitochondria in control of hypothalamic metabolic circuits / C.M. Nasrallah and T.L. Horvath -- Mitochondria anchored at the synapse / G.A. Spirou, D. Jackson and G.A. Perkins -- Neuronal



mitochondria are different : relevance to neurodegenerative disease / S.B. Berman and J.M. Hardwick -- PINK1 as a sensor for mitochondrial function : dual roles / E.K. Steer, M.K. Dail and C.T. Chu -- A get-together to tear it apart : the mitochondrion meets the cellular turnover machinery / G.-L. McLelland and E.A. Fon -- Mitochondrial involvement in neurodegenerative dementia / L. Bonanni, V. Frazzini, A. Thomas and M. Onofrj -- Neuronal mitochondria as a target for the discovery and development of new therapeutics / V.K. Gribkoff -- Mitochondria as a therapeutic target for Alzheimer's disease / C.H.-L. Hung, S.S.-Y. Chung, S.M.-Y. Lee and R.C.-C. Chang -- Mitochondria in Parkinson disease / G. Arena and E.M. Valente -- Therapeutic targeting of neuronal mitochondria in brain injury / H.M. Yonutas, E.D. Hall and P.G. Sullivan -- The use of fibroblasts from patients with inherited mitochondrial disorders for pathomechanistic studies and evaluation of therapies / D. Soiferman and A. Saada.