1.

Record Nr.

UNINA9910812923603321

Autore

Piatigorsky Joram

Titolo

Gene sharing and evolution : the diversity of protein functions / / Joram Piatigorsky

Pubbl/distr/stampa

Cambridge, Mass., : Harvard University Press, 2007

ISBN

0-674-04212-3

Edizione

[1st ed.]

Descrizione fisica

1 online resource (337 p.)

Classificazione

WG 1940

Disciplina

572/.6

Soggetti

Genetic regulation

Proteins - Evolution

Eye - Molecular aspects

Crystalline lens

Lingua di pubblicazione

Inglese

Formato

Materiale a stampa

Livello bibliografico

Monografia

Note generali

Bibliographic Level Mode of Issuance: Monograph

Nota di bibliografia

Includes bibliographical references (p. 241-305) and index.

Nota di contenuto

Frontmatter -- Contents -- Illustrations -- Preface -- 1. What Is "Gene Sharing"? -- 2. Multifunctions and Functional Shifts: Echos from the Past -- 3. The Elusive Concept of a "Gene" -- 4. Eyes and Lenses: Gene Sharing by Crystallins -- 5. The Enigmatic "Corneal Crystallins": Putative Cases of Gene Sharing -- 6. Gene Sharing as a Common Event: Many Multifunctional Proteins -- 7. Gene Sharing during Gene Expression -- 8. Gene Sharing As a Dynamic Evolutionary Process: Antifreeze Proteins and Hemoglobins -- 9. Gene Duplication and the Evolution of New Functions -- 10. Gene Sharing and Systems Biology: Implications and Speculations -- 11. Recapitulations: Ambiguities and Possibilities -- Glossary -- References -- Index

Sommario/riassunto

In Gene Sharing and Evolution Piatigorsky explores the generality and implications of gene sharing throughout evolution and argues that most if not all proteins perform a variety of functions in the same and in different species, and that this is a fundamental necessity for evolution.