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Record Nr. |
UNINA9910812788203321 |
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Titolo |
Therapeutic proteins : strategies to modulate their plasma half-lives / / edited by Roland Kontermann |
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Pubbl/distr/stampa |
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Weinheim, Germany, : Wiley-Blackwell, 2012 |
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ISBN |
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9786613454225 |
9783527644780 |
3527644784 |
9781283454223 |
128345422X |
9783527644827 |
3527644822 |
9783527644797 |
3527644792 |
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Edizione |
[1st ed.] |
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Descrizione fisica |
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1 online resource (374 p.) |
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Altri autori (Persone) |
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Disciplina |
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Soggetti |
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Protein drugs - Design |
Proteins - Therapeutic use |
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Lingua di pubblicazione |
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Formato |
Materiale a stampa |
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Livello bibliografico |
Monografia |
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Note generali |
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Description based upon print version of record. |
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Nota di bibliografia |
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Includes bibliographical references and index. |
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Nota di contenuto |
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pt. 1. General information -- pt. 2. Half-life extension through chemical and post-translational modifications -- pt. 3. Half-life modulation involving recycling by the neonatal Fc receptor -- pt. 4. Half-life extension with pharmaceutical formulations. |
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Sommario/riassunto |
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For this ready reference, the internationally renowned authority in the field, Roland Kontermann, has assembled a team of outstanding contributors from industry and academia to convey the worldwide knowledge on modifying therapeutic proteins in order to optimize their pharmacological potential. The result is a comprehensive work covering all approaches and aspects of the topic in one handy volume, making this indispensable reading for companies and research institutions working on the development of biopharmaceuticals. |
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