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1. |
Record Nr. |
UNINA9910298640403321 |
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Autore |
Sharp Thomas Harry |
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Titolo |
Biomolecular imaging at high spatial and temporal resolution in vitro and in vivo / / Thomas Harry Sharp |
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Pubbl/distr/stampa |
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Cham [Switzerland] : , : Springer, , 2014 |
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ISBN |
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Edizione |
[1st ed. 2014.] |
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Descrizione fisica |
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1 online resource (xviii, 150 pages) : illustrations (some color) |
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Collana |
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Springer Theses, Recognizing Outstanding Ph.D. Research, , 2190-5053 |
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Disciplina |
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Soggetti |
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Electron microscopy |
Cryobiochemistry |
Peptides - Structure |
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Lingua di pubblicazione |
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Formato |
Materiale a stampa |
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Livello bibliografico |
Monografia |
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Note generali |
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Nota di bibliografia |
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Includes bibliographical references. |
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Nota di contenuto |
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Biomolecules & Microscopy -- Materials and Methods -- Experimental Methods -- Imaging Methods -- Experimental Results -- Towards an Atomistic Structure of a De Novo Designed Peptide Fibre -- Developing Novel Probes for Correlative Light Electron Microscopy. |
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Sommario/riassunto |
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As part of a collaboration between two different groups in chemistry and biochemistry, Thom Sharp presents here his thesis work on the development of new methods for cryoelectron microscopy. Throughout his PhD, Thom had to master a whole range of techniques including modelling, molecular biology and microscopy. Using these skills to tackle an outstanding problem, the pursuit of high-resolution structures of peptide-based materials, Thom highlights in this thesis his newly developed methods for analysing and processing this particular type of electron microscopy data. This thesis gives the first molecular description of a de-novo designed peptide-based material. In general, this research will have a huge impact on the peptide assembly field, and also in electron microscopy as it introduces new methods and approaches, all of which are Thom's inventions and are described in this thesis. |
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2. |
Record Nr. |
UNINA9910812752403321 |
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Autore |
Canary Richard Douglas |
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Titolo |
Homotopy equivalences of 3-manifolds and deformation theory of Kleinian groups / / Richard D. Canary, Darryl McCullough |
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Pubbl/distr/stampa |
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Providence, Rhode Island : , : American Mathematical Society, , 2004 |
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©2004 |
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ISBN |
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Descrizione fisica |
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1 online resource (238 p.) |
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Collana |
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Memoirs of the American Mathematical Society, , 0065-9266 ; ; Volume 172, Number 812 |
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Disciplina |
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Soggetti |
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Three-manifolds (Topology) |
Homotopy equivalences |
Low-dimensional topology |
Kleinian groups |
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Lingua di pubblicazione |
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Formato |
Materiale a stampa |
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Livello bibliografico |
Monografia |
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Note generali |
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"Volume 172, Number 812 (first of 4 numbers)." |
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Nota di bibliografia |
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Includes bibliographical references and index. |
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Nota di contenuto |
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""Contents""; ""Preface""; ""Chapter 1. Introduction""; ""1.1. Motivation""; ""1.2. The main theorems for Haken 3-manifolds""; ""1.3. The main theorems for reducible 3-manifolds""; ""1.4. Examples""; ""Chapter 2. Johannson's Characteristic Submanifold Theory""; ""2.1. Fibered 3-manifolds""; ""2.2. Boundary patterns""; ""2.3. Admissible maps and mapping class groups""; ""2.4. Essential maps and useful boundary patterns""; ""2.5. The classical theorems""; ""2.6. Exceptional fibered 3-manifolds""; ""2.7. Vertical and horizontal surfaces and maps""; ""2.8. Fiber-preserving maps"" |
""2.9. The characteristic submanifold""""2.10. Examples of characteristic submanifolds""; ""2.11. The Classification Theorem""; ""2.12. Miscellaneous topological results""; ""Chapter 3. Relative Compression Bodies and Cores""; ""3.1. Relative compression bodies""; ""3.2. Minimally imbedded relative compression bodies""; ""3.3. The maximal incompressible core""; ""3.4. Normally imbedded relative compression bodies""; ""3.5. The normal core and the useful core""; ""Chapter 4. Homotopy Types""; ""4.1. Homotopy equivalences preserve usefulness""; ""4.2. Finiteness of homotopy types"" |
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""Chapter 5. Pared 3-Manifolds""""5.1. Definitions and basic properties""; ""5.2. The topology of pared manifolds""; ""5.3. The characteristic submanifold of a pared manifold""; ""Chapter 6. Small 3-Manifolds""; ""6.1. Small manifolds and small pared manifolds""; ""6.2. Small pared homotopy types""; ""Chapter 7. Geometrically Finite Hyperbolic 3-Manifolds""; ""7.1. Basic definitions""; ""7.2. Quasiconformal deformation theory: a review""; ""7.3. The Parameterization Theorem""; ""Chapter 8. Statements of Main Theorems""; ""8.1. Statements of Main Topological Theorems"" |
""8.2. Statements of Main Hyperbolic Theorem and Corollary""""8.3. Derivation of hyperbolic results""; ""Chapter 9. The Case When There Is a Compressible Free Side""; ""9.1. Algebraic lemmas""; ""9.2. The finite-index cases""; ""9.3. The infinite-index cases""; ""Chapter 10. The Case When the Boundary Pattern Is Useful""; ""10.1. The homomorphism Î?""; ""10.2. Realizing homotopy equivalences of I-bundles""; ""10.3. Realizing homotopy equivalences of Seifert-fibered manifolds""; ""10.4. Proof of Main Topological Theorem 2""; ""Chapter 11. Dehn Flips"" |
""Chapter 12. Finite Index Realization For Reducible 3-Manifolds""""12.1. Homeomorphisms of connected sums""; ""12.2. Reducible 3-manifolds with compressible boundary""; ""12.3. Reducible 3-manifolds with incompressible boundary""; ""Chapter 13. Epilogue""; ""13.1. More topology""; ""13.2. More geometry""; ""Bibliography""; ""Index""; ""A""; ""B""; ""C""; ""D""; ""E""; ""F""; ""G""; ""H""; ""I""; ""J""; ""K""; ""L""; ""M""; ""N""; ""O""; ""P""; ""Q""; ""R""; ""S""; ""T""; ""U""; ""V""; ""W"" |
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