Congenital disorders of erythropoiesis : in memory of the late Fred Stohlman / / editors, Ruth Porter, David W. Fitzsimons

• Record Nr.: UNINA9910812684103321
• Pubbl/distr/stampa: Amsterdam ; ; Oxford, : Elsevier, 1976; Amsterdam ; ; Oxford : , : Elsevier, , 1976
• ISBN: 9786613693877; 9781280783487; 1280783486; 9780470720196; 0470720190; 9780470717875; 0470717874
• Edizione: [1st ed.]
• Descrizione fisica: 1 online resource (418 pages) : illustrations
• Collana: CIBA Foundation symposium ; ; 40 (new ser.)
• Altri autori (Persone): PorterRuth; FitzSimonsDavid W; StohlmanFrederick
• Disciplina: 616.1/51043
• Soggetti: Erythrocytes; Blood - Diseases
• Lingua di pubblicazione: Inglese
• Formato: Materiale a stampa
• Livello bibliografico: Monografia
• Note generali: 'Symposium on Congenital Disorders of Erythropoiesis held at the Ciba Foundation, London, 12-14th March, 1975' - Participants.
• Nota di bibliografia: Includes bibliographical references and indexes.
• Nota di contenuto: Congenital Disorders of Erythropoiesis; Contents; Chairman's opening remarks; Cellular kinetics of erythropoiesis; Discussion; Regulation of fetal and adult erythropoiesis; Discussion; Embryonic erythropoiesis: some experimental systems; Discussion; Oxygen dissociation studies of red cells from chicken, mouse and human embryos; Discussion; General discussion I; Diamond-Blackfan anaemia; Discussion; Fanconi anaemia; Fanconi anaemia: cellular abnormalities and clinical predisposition to malignant disease; Discussion of the two preceding papers; Congenital dyserythropoietic anaemia type I : clinical and experimental aspects Discussion; Congenital dyserythropoietic anaemia type I1 (Hempas); Discussion; Congenital dyserythropoietic anaemias : electron ; microscopy; Discussion; Pathophysiology of the anaemia in thalassaemia; Discussion; The morphology and kinetics of erythropoiesis in homozygous β-thalassaemia; Discussion; The molecular defect in thalassaemia; Discussion; Cytogenetics of Fanconi anaemia and related chromosome disorders; Discussion; Fetal haemoglobin synthesis; Discussion; Regulation of globin gene expression; Discussion; General discussion II: Clinical management Conservative management; Androgen therapy in aplastic anaemia in childhood; Chelating agents; Bone marrow transplants; Genetic manipulation; Antenatal diagnosis; Concluding remarks; Index of contributors; Subject index
• Sommario/riassunto: The Novartis Foundation Series is a popular collection of the proceedings from Novartis Foundation Symposia, in which groups of leading scientists from a range of topics across biology, chemistry and medicine assembled to present papers and discuss results. The Novartis Foundation, originally known as the Ciba Foundation, is well known to scientists and clinicians around the world.