Submolecular biology and cancer : in honour of Albert Szent-Györgyi on the occasion of his 85th birthday / / [editors, G. E. W. Wolstenholme, D. W. Fitzsimons, Julie Whelan]

• Record Nr.: UNINA9910812683103321
• Pubbl/distr/stampa: Amsterdam ; ; New York : , : Excerpta Medica, , 1979
• ISBN: 9786613694195; 9780470720493; 0470720492; 9781280783807; 128078380X; 9780470718186; 0470718188
• Edizione: [1st ed.]
• Descrizione fisica: 1 online resource (ix, 349 pages) : illustrations, charts
• Collana: Ciba Foundation symposium (new series) ; ; 67
• Altri autori (Persone): WolstenholmeG. E. W (Gordon Ethelbert Ward); FitzSimonsDavid W; WhelanJulie; Szent-GyörgyiAlbert <1893-1986.>
• Disciplina: 616.9/94/00157488
• Soggetti: Cancer - Research; Electron mobility; Glyoxal; Molecular biology
• Lingua di pubblicazione: Inglese
• Formato: Materiale a stampa
• Livello bibliografico: Monografia
• Note generali: "Symposium on Submolecular Biology and Cancer, held at the Ciba Foundation, London, 25th-27th September 1978"--Participants page.; "In honour of Albert Szent-Györgyi on the occasion of his 85th birthday."
• Nota di bibliografia: Includes bibliographical references and indexes.
• Nota di contenuto: Intro -- Submolecular Biology and Cancer -- Contents -- Introduction -- The living state and cancer -- A note on cancer and possible relationships to submolecular biology -- Energy bands and charge transfer in proteins -- Discussion -- Electronic structure of proteins and DNA: solid-state aspects -- Discussion -- The mechanism of conduction in proteins -- Discussion -- Electronic and dielectric ; properties of protein - methylglyoxal complexes -- Discussion -- Free radicals in cancer -- Discussion -- Whole-body nuclear magnetic resonance scanning: n.m.r. studies of tumour cells -- Discussion -- Quantum chemical investigations of charge- transfer interactions in relation to the electronic theory of cancer -- Discussion -- The search for new cancerostatic agents -- Discussion -- Thermal copoly(amino acids) as inhibitors of glyoxalase I -- Discussion -- Interactions of methylglyoxal with methylamine -- Discussion -- Methylglyoxal production in human blood -- Discussion -- Formation and properties of reactive aldehydes -- Discussion -- Biological activity of methylglyoxal and related aldehydes -- Discussion -- Carcinostatic activity of methylglyoxal and related substances in tumour-bearing mice -- Discussion -- Biochemical studies of transient intermediates in relation to chemical carcinogenesis -- Discussion -- General discussion -- Index contributors -- Subject index.
• Sommario/riassunto: The Novartis Foundation Series is a popular collection of the proceedings from Novartis Foundation Symposia, in which groups of leading scientists from a range of topics across biology, chemistry and medicine assembled to present papers and discuss results. The Novartis Foundation, originally known as the Ciba Foundation, is well known to scientists and clinicians around the world.