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Record Nr. |
UNINA9910811438303321 |
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Titolo |
Pharmaceutical toxicology in practice : a guide for non-clinical development / / edited by Alberto Lodola, Jeanne Stadler |
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Pubbl/distr/stampa |
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Hoboken, N.J., : John Wiley & Sons, c2011 |
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ISBN |
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9786613072238 |
9780470922729 |
0470922729 |
9781283072236 |
1283072238 |
9780470909911 |
0470909919 |
9780470909904 |
0470909900 |
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Edizione |
[1st ed.] |
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Descrizione fisica |
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1 online resource (268 p.) |
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Altri autori (Persone) |
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LodolaAlberto |
StadlerJeanne |
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Disciplina |
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Soggetti |
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Lingua di pubblicazione |
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Formato |
Materiale a stampa |
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Livello bibliografico |
Monografia |
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Note generali |
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Description based upon print version of record. |
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Nota di bibliografia |
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Includes bibliographical references and index. |
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Nota di contenuto |
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The regulatory environment / Claudio Bernardi and Marco Brughera --Toxicological development : roles and responsibilities / Franck Chuzel and Bernard Ruty -- Contract research organizations / Maurice Cary -- Safety pharmacology / Claudio Arrigoni and Valeria Perego -- Formulations, impurities and toxicokinetics / Claude Charuel -- General toxicology / Alberto Lodola -- Genetic toxicology / Peggy Guzzie-Peck, Jennifer Sasaki, and Sandy Weiner -- Developmental and reproductive toxicology / Jeanne Stadler -- Data analysis, report writing and regulatory documentation / Monique Y. Wells -- Risk management / Alberto Lodola. |
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Sommario/riassunto |
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This book describes, with references to key source materials, the background to, and conduct of, the principal nonclinical studies that are central to drug development. The chapters provide an |
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understanding of the key components of the preclinical phase of drug development with a hands-on description, with core chapters addressing study conduct, types, and reporting. As such, it is a practical guide through toxicology testing and an up-to-date reference on current issues, new developments, and future directions in toxicology. Opening with a practical description of toxicology and its role in t |
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