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Record Nr. |
UNINA9910810323903321 |
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Titolo |
Controlled drug delivery : the role of self-assembling multi-task excipients / / edited by M. A. Mateescu, P. Ispas-Szabo, E. Assaad |
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Pubbl/distr/stampa |
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Cambridge, [England] : , : Woodhead Publishing, , 2015 |
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©2015 |
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ISBN |
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1-908818-67-0 |
1-907568-45-X |
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Descrizione fisica |
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1 online resource (269 p.) |
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Collana |
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Woodhead Publishing Series in Biomedicine ; ; Number 74 |
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Disciplina |
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Soggetti |
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Drug delivery systems |
Excipients |
Self-organizing systems |
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Lingua di pubblicazione |
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Formato |
Materiale a stampa |
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Livello bibliografico |
Monografia |
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Note generali |
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Description based upon print version of record. |
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Nota di bibliografia |
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Includes bibliographical references at the end of each chapters and index. |
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Nota di contenuto |
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Front Cover; Controlled Drug Delivery; Copyright Page; Contents; List of figures; List of tables; Biography for book; 1 The concept of self-assembling and the interactions involved; 1.1 The concept of self-assembling; 1.1.1 The concept of self-assembling by association/interaction processes; 1.2 The nature of forces and types of interactions involved in self-assembly of macromolecules; 1.3 Hydrogels and their role in drug conception and development; 1.3.1 Organogels and micelles for drug delivery; 1.4 Self-assembling phenomena in solid dosage forms |
1.4.1 Hydrogen association and flexibility of chains1.4.2 Ionically stabilized excipients; 1.4.2.1 Two-speed self-assembled monolithic devices; 1.4.3 Hydrophobic stabilization of excipients and drug release mechanisms; 1.4.3.1 The concept of self-assembling by inclusion processes; 1.4.3.2 Inclusion complexes of starch with fatty bioactive agents; 1.4.3.3 Inclusion complexes and hydrophobic assembly of starch excipients; 1.5 Conclusions; References; 2 Starch and derivatives as pharmaceutical excipients; 2.1 General aspects; 2.2 Structural considerations |
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2.3 Self-assembling in physically modified starches2.3.1 Pregelatinized starch; 2.3.2 Multifunctional excipient: binder-filler and binder-disintegrant; 2.3.3 Extruded starch; 2.3.4 Soft starch capsules; 2.3.5 Hard capsules; 2.3.6 Starch films as functional coatings; 2.3.7 Starch microspheres and nanospheres in drug delivery; 2.3.8 Starch complexes; 2.3.9 Conclusions; 2.4 Chemically modified starches and their self-assembling; 2.4.1 Self-assembling in cross-linked starches; 2.4.2 Starch ethers; 2.4.3 Ionic starches and their self-assembling features; 2.4.3.1 CMS as pH-responsive excipient |
2.4.3.2 Cationic starch2.4.4 Conclusions; References; 3 Chitosan and its derivatives as self-assembled systems for drug delivery; Abbreviations; 3.1 Introduction; 3.2 Unmodified chitosan-self-assembled thermogels; 3.2.1 Mechanism of chitosan thermogelation; 3.2.2 Chitosan thermogels; 3.3 Amphiphilic chitosan derivatives; 3.3.1 Alkylated chitosan; 3.3.2 Acylated chitosan; 3.3.2.1 Acylated chitosan; 3.3.2.2 Acylated chitosan oligosaccharides; 3.3.3 Cholesterol-modified chitosan; 3.3.4 Cholic and deoxycholic acid-modified chitosan; 3.3.5 5β-Cholanic acid-modified chitosan |
3.3.6 Phthaloylchitosan and other hydrophobically modified chitosans3.3.7 Hydrophobic drug-grafted chitosan; 3.4 Amphiphilic/amphoteric chitosan derivatives; 3.4.1 Hydrophobically modified carboxylated chitosan; 3.4.1.1 Alkyl-modified carboxylated chitosan; 3.4.1.2 Acyl-modified carboxylated chitosan; 3.4.1.3 Cholesterol-modified carboxylated chitosan; 3.4.1.4 Deoxycholic acid-modified carboxylated chitosan; 3.4.2 Hydrophobically modified sulfated chitosan; 3.5 Conclusion; References; 4 Chitosan-based polyelectrolyte complexes as pharmaceutical excipients; Abbreviations |
4.1 Introduction to chitosan-based polyelectrolyte complexes |
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Sommario/riassunto |
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In complex macromolecules, minor modifications can generate major changes, due to self-assembling capacities of macromolecular or supramolecular networks. Controlled Drug Delivery highlights how the multifunctionality of several materials can be achieved and valorized for pharmaceutical and biopharmaceutical applications. Topics covered in this comprehensive book include: the concept of self-assembling; starch and derivatives as pharmaceutical excipients; and chitosan and derivatives as biomaterials and as pharmaceutical excipients. Later chapters discuss polyelectrolyte complexes as excipient |
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2. |
Record Nr. |
UNINA9910983362803321 |
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Titolo |
Emerging VLSI Devices, Circuits and Architectures : Proceedings of the 27th International Symposium, VDAT 2023 / / edited by Anu Gupta, Jai Gopal Pandey, Nitin Chaturvedi, Devesh Dwivedi |
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Pubbl/distr/stampa |
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Singapore : , : Springer Nature Singapore : , : Imprint : Springer, , 2025 |
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ISBN |
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Edizione |
[1st ed. 2025.] |
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Descrizione fisica |
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1 online resource (XX, 350 p. 296 illus., 200 illus. in color.) |
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Collana |
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Lecture Notes in Electrical Engineering, , 1876-1119 ; ; 1234 |
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Disciplina |
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Soggetti |
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Electronic circuits |
Computer engineering |
Computer networks |
Electronic Circuits and Systems |
Computer Engineering and Networks |
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Lingua di pubblicazione |
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Formato |
Materiale a stampa |
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Livello bibliografico |
Monografia |
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Nota di bibliografia |
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Includes bibliographical references and index. |
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Nota di contenuto |
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Analysis of SQNR Degradation in Noise-Shaped SAR Analog-to-Digital Converters at High Input Signal Amplitudes -- An improved clock booster circuit suitable for boost converters in energy harvesting environments -- A Current-Mode-Logic Based PFD-Charge Pump Circuit for Low Reference Spur PLLs -- An Energy Efficient Mixed Logic 2-to-4 Decoder for Embedded Memory Applications -- Analysis and Modeling of Self-Heating and Substrate Induced Transitions in 5 nm Stacked Nanosheet FET -- Chemisorption Analysis of NOx Sensor Using NF/Pr-AGNR: A DFT Investigation -- Design and Analysis of Differential Configuration based Active Inductor for 5G Sub-6GHz Applications -- A Dual-Mode High-Frequency Grounded Memristor Emulator Circuit -- Demonstration of Doped-HfO2 Ferroelectric based Double Layer Stacked NC FinFET -- High Precision Programmable Thermistor Linearization ASIC for Electro-Optical Payload Applications -- Design and Analysis of Low-Power Protection Circuits for LDO Regulators -- Preventing Costly Iterations by Delivering SoC Congestion Aware Standard Cell Lib using Pin Accessibility Checker -- High Throughput |
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Multiple Device Diagnosis System for Hierarchical Test Designs -- Characterization of Multi-Vt Transistors for Analog IC Design in Sub-nanometer Technologies -- Design and Analysis of Modified Strong Arm Latch Comparator with Reduced Kickback Noise -- Construction of non-rectangular floor plans for properly triangulated planar graphs. |
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Sommario/riassunto |
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This book constitutes the proceedings of the 27th International Symposium on VLSI Design and Test, VDAT 2023. The 32 regular papers and 16 short papers presented in this book are carefully reviewed and selected from 220 submissions. They are organized in topical sections as follows: Low-Power Integrated Circuits and Devices; FPGA-Based Design and Embedded Systems; Memory, Computing, and Processor Design; CAD for VLSI; Emerging Integrated Circuits and Systems; VLSI Testing and Security; and System-Level Design. |
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