Transport processes in pharmaceutical systems / / edited by Gordon L. Amidon, Ping I. Lee, Elizabeth M. Topp

• Record Nr.: UNINA9910809506703321
• Pubbl/distr/stampa: New York : , : M. Dekker, , 2000
• ISBN: 0-429-22188-6; 1-135-55064-6; 0-8247-4632-5; 0-203-90947-X; 9786610100361; 1-280-10036-2
• Descrizione fisica: 1 online resource (727 p.)
• Collana: Drugs and the pharmaceutical sciences ; ; v. 102
• Altri autori (Persone): AmidonGordon L; LeePing I. <1948-.>; ToppElizabeth M. <1957->
• Disciplina: 615.7
• Soggetti: Pharmacokinetics; Biological transport; Drug delivery systems; Transport theory
• Lingua di pubblicazione: Inglese
• Formato: Materiale a stampa
• Livello bibliografico: Monografia
• Note generali: Description based upon print version of record.
• Nota di bibliografia: Includes bibliographical references and index.
• Nota di contenuto: Front Cover; Preface; Contents; Contributors; Principles of Mass Transfer; Analytical Solutions to Mass Transfer; Pharmacokinetics: Model Structure and Transport Systems; Experimental Methods to Evaluate Diffusion Coefficients and Investigate Transport Processes of Pharmaceutical Interest; Dissolution of Pharmaceuticals in Simple and Complex Systems; Biological Transport Phenomena in the Gastrointestinal Tract: Cellular Mechanisms; Improving Oral Drug Transport via Prodrugs; Quantitative Approaches to Delineate Passive Transport Mechanisms in Cell Culture Monolayers; Barriers to Drug Transport in Ocular EpitheliaPredicting Oral Drug Absorption in Humans; Controlled Release Osmotic Drug Delivery Systems for Oral Applications; Transport in Polymer Systems; Synthesis ; and Properties of Hydrogels Used for Drug Delivery; Stimuli-Modulated Delivery Systems; Properties of Solids That Affect Transport; Heat and Mass Transfer in Low Pressure Gases: Applications to Freeze Drying; Heat and Mass Transport: Hygroscopicity; Back Cover
• Sommario/riassunto: This cutting-edge reference clearly explains pharmaceutical transport phenomena, demonstrating applications ranging from drug or nutrient uptake into vesicle or cell suspensions, drug dissolution and absorption across biological membranes, whole body kinetics, and drug release from polymer reservoirs and matrices to heat and mass transport in freeze-drying and hygroscopicity.<BR>Focuses on practical applications of drug delivery from a physical and mechanistic perspective, highlighting biological systems.<BR>Written by more than 30 international authorities in the field, Transport Processes in