1.

Record Nr.

UNINA9910809233503321

Titolo

Chemical biology in regenerative medicine : bridging stem cells and future therapies / / edited by Charles C. Hong, Jijun Hao, and Ada Ao

Pubbl/distr/stampa

Chichester, England : , : Wiley, , 2014

©2014

ISBN

1-118-69575-5

1-118-69574-7

1-118-69576-3

Descrizione fisica

1 online resource (236 p.)

Disciplina

616.02/774

Soggetti

Stem cells

Lingua di pubblicazione

Inglese

Formato

Materiale a stampa

Livello bibliografico

Monografia

Note generali

Description based upon print version of record.

Nota di bibliografia

Includes bibliographical references at the end of each chapters and index.

Nota di contenuto

Wnt signaling in regulation of stem cells / David T. Paik and Antonis K. Hatzopoulos -- Directed cardiomyogenesis of pluripotent stem cells / Jeffery B. Bylund & Antonis K. Hatzopoulos -- Chemical genetics in cardiomyocyte generation / Daqing Jin, Qiao Li and Tao P. Zhong -- Challenges and new directions for cardiac reprogramming / Young-Jae Nam and Nikhil Munshi -- Comparative analysis of adult stem cell niches / Bryan A. Fioret & Antonis K. Hatzopoulos -- Chemicals and stem cells for promoting regeneration / Bastakoty, Dikshya, Saraswati, Sarika, Young, Pampee -- Chemically induced pluripotent stem cells (CiPSC) : a potential chemical biological breakthrough in reprogramming? / Calvin C. Sheng, Jijun Hao, and Charles C. Hong -- An introduction to cellular reprogramming : the plasticity of cell fates and identities / Kelly P. Smith -- Chemicals facilitating reprogramming / Zhong-Dong Shi, Federico González, and Danwei Huangfu -- Chemicals facilitating reprogramming : targeting the SAM binding site to identify novel methyltransferase inhibitors / Jeong-Do Kim, Jong S. Rim, Robert B. Crochet, Yong-Hwan Lee, Jaroslaw Staszkiewicz, Ru Gao, Kenneth J. Eilertsen -- Biomaterials for directed differentiation / Xintong Wang, Angela L. Zachman, Simon Maltais, Hak-Joon Sung -- Practicalities to translation from the clinic to the market / Devyn M.



Smith.

Sommario/riassunto

Chemical Biology in Regenerative Medicine: Bridging Stem Cells and Future Therapies  The field of regenerative medicine has advanced at a rapid pace and this comprehensive summary of new developments is a timely contribution to the field as clinical trials have begun to assess the safety and efficacy of cell-based therapies.  In Chemical Biology in Regenerative Medicine, an international team of experts provides an overview of progress towards clinical application in the areas of transplantation (allogenic and autologous), manipulation of niche environment and homing, and cell reprogramming (