1.

Record Nr.

UNINA9910806194803321

Titolo

Challenges and Solutions Against Visceral Leishmaniasis [[electronic resource] /] / edited by Angamuthu Selvapandiyan, Ruchi Singh, Niti Puri, Nirmal K. Ganguly

Pubbl/distr/stampa

Singapore : , : Springer Nature Singapore : , : Imprint : Springer, , 2023

ISBN

981-9969-99-9

Edizione

[1st ed. 2023.]

Descrizione fisica

1 online resource (XXI, 449 p. 36 illus., 34 illus. in color.)

Disciplina

571.999

Soggetti

Parasitology

Drugs - Design

Pharmaceutical chemistry

Epidemiology

Structure-Based Drug Design

Pharmaceutics

Lingua di pubblicazione

Inglese

Formato

Materiale a stampa

Livello bibliografico

Monografia

Nota di contenuto

Module 1_Epidemiology and Surveillances -- Module 2_Omics and Advancement in Diagnosis -- Module 3_Genetics -- Module 4_New Drug Discovery Opportunity -- Module 5_Immunity and Vaccine Development.

Sommario/riassunto

This book comprehensively reviews the epidemiology and surveillance strategies of Visceral Leishmaniasis, and the latest developments in disease diagnosis, drug discovery, and vaccine development. The initial chapters cover the epidemiology features and spatial distribution of Visceral Leishmaniasis. The book further discusses the manifestations of HIV-Visceral Leishmaniasis infection on the immunopathogenesis, diagnosis, and therapeutic response. It analyzes the role of different proteomic technologies in understanding the parasite development, survival, drug resistance mechanisms, host-pathogen interactions, and the development of new therapeutic approaches. The book concludes by discussing recent advancements in vaccine development for Visceral Leishmaniasis. It discusses the promising vaccine candidate, their developmental status, current challenges, and prospects for rational



vaccine development against Leishmania. This book is an invaluable source of information for students, and researchers working to understand the Leishmania biology, and drug development.