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Record Nr. |
UNINA9910806162503321 |
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Titolo |
Substance P in the nervous system |
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Pubbl/distr/stampa |
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London, : Pitman |
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Summit, N.J., USA, : Distributed in North America by Ciba Pharmaceutical Co., Medical Education Administration, 1982 |
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ISBN |
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9786613694461 |
9781280784071 |
1280784075 |
9780470720738 |
0470720735 |
9780470718421 |
0470718420 |
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Edizione |
[1st ed.] |
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Descrizione fisica |
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1 online resource (362 p.) |
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Collana |
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Ciba Foundation symposium ; ; 91 |
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Altri autori (Persone) |
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Disciplina |
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Soggetti |
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Lingua di pubblicazione |
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Formato |
Materiale a stampa |
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Livello bibliografico |
Monografia |
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Note generali |
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"Editors: Ruth Porter (organizer) and Maeve O'Connor"--P. v. |
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Nota di bibliografia |
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Includes bibliographical references and indexes. |
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Nota di contenuto |
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Substance P in the nervous system; Contents; Introduction; Chemical neurotransmission-yesterday and today; Role of substance P as a sensory transmitter in spinal cord and sympathetic ganglia; Discussion; Substance P in peripheral sensory processes; Discussion; Localization of substance P in neuronal pathways; Discussion; Distribution of substance P in brain and periphery and its possible role as a co-transmitter; Discussion; Regulation of substance P expression and metabolism in vivo and in vitro; Discussion; GENERAL DISCUSSION; Coexistence of transmitters |
Substance P in nerve tissue in the gut Discussion; Biosynthesis, axonal transport and turnover of neuronal substance P; Discussion; Enzymic inactivation of substance P in the central nervous system; Discussion; Substance P receptors in the nervous system and possible receptor subtypes; Discussion; Relation of substance P to pain transmission: |
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neurophysiological evidence; Discussion; Substance P in nociceptive sensory neurons; Discussion; If substance P fails to fulfil the criteria as a neurotransmitter in somatosensory afferents, what might be its function?; Discussion |
Modulation of cholinergic transmission by substance PDiscussion; The striatonigral substance P pathway and dopaminergic mechanisms; Discussion; Relation of substance P to stress and catecholamine metabolism; Discussion; Behavioural effects of substance P through dopaminergic pathways in the brain; Discussion; FINAL GENERAL DISCUSSION; Substance P antagonists; tumour cell lines and substance P; substance P and other tachykinins; substance P and clinical pain syndromes; substance P and neuronal systems; Index of contributors; Subject index |
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Sommario/riassunto |
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The Novartis Foundation Series is a popular collection of the proceedings from Novartis Foundation Symposia, in which groups of leading scientists from a range of topics across biology, chemistry and medicine assembled to present papers and discuss results. The Novartis Foundation, originally known as the Ciba Foundation, is well known to scientists and clinicians around the world. |
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