1.

Record Nr.

UNINA9910799959403321

Titolo

Real options in engineering design, operations, and management / / edited by Harriet Black Nembhard, Mehmet Aktan

Pubbl/distr/stampa

Boca Raton : , : CRC Press, , 2010

ISBN

0-429-14181-5

1-282-31211-1

1-4200-7170-X

9786612312113

Descrizione fisica

1 online resource (258 p.)

Altri autori (Persone)

NembhardHarriet Black

AktanMehmet

Disciplina

620

620.0042

620/.0042

Soggetti

Engineering design - Management

Operations research

Real options (Finance)

Lingua di pubblicazione

Inglese

Formato

Materiale a stampa

Livello bibliografico

Monografia

Note generali

Description based upon print version of record.

Nota di bibliografia

Includes bibliographical references and index.

Nota di contenuto

Front cover; Contents; Preface; Editors; Contributors; Chapter 1. Introduction; Chapter 2. Real Options in Practice; Chapter 3. Origins of Real Options in Engineering; Chapter 4. Real Options in Manufacturing Operations; Chapter 5. Real Options Valuation for Quality Improvement; Chapter 6. Real Options in Outsourcing; Chapter 7. Barriers to Real Options Adoption and Use in Architecture, Engineering, and Construction Project Management Practice; Chapter 8. Identifying Real Options to Improve the Design of Engineering Systems

Chapter 9. Real Options in Underground Mining Systems Planning and DesignChapter 10. Real Options in Engineering Systems Design; Chapter 11. Real Options Model for Workforce Cross-Training; Chapter 12. Real Options Design for Sustainable Product Quality Management; Chapter 13. Real Options in Nanotechnology R&D; Chapter 14. Real Options-Based Analysis in Pharmaceutical Partnerships for Research and Development; Chapter 15. Hands-On Applications: Real Option



Super Lattice Solver Software; Index; Back cover

Sommario/riassunto

Given that engineering flexibility can potentially provide a competitive advantage, the question then becomes: Precisely how valuable is this flexibility? However, traditional methods often fail to accurately capture the economic value of investments in an environment of widespread uncertainty and rapid change. The real options method represents the new state-of-the-art technique for valuation and management of strategic investments, enabling corporate decision-makers to leverage uncertainty and limit downside risk. Real Options in Engineering Design, Operations, and M

2.

Record Nr.

UNINA9910298278803321

Titolo

Influenza Pathogenesis and Control - Volume II / / edited by Michael B. A. Oldstone, Richard W. Compans

Pubbl/distr/stampa

Cham : , : Springer International Publishing : , : Imprint : Springer, , 2015

ISBN

3-319-11158-2

Edizione

[1st ed. 2015.]

Descrizione fisica

1 online resource (478 p.)

Collana

Current Topics in Microbiology and Immunology, , 0070-217X ; ; 386

Disciplina

610

613

614.44

615372

616.9

616079

Soggetti

Immunology

Vaccines

Infectious diseases

Health promotion

Vaccine

Infectious Diseases

Health Promotion and Disease Prevention

Lingua di pubblicazione

Inglese

Formato

Materiale a stampa

Livello bibliografico

Monografia

Note generali

Description based upon print version of record.



Nota di bibliografia

Includes bibliographical references and index.

Nota di contenuto

The role of cytokine responses during influenza virus pathogenesis and potential therapeutic options -- Innate immune sensing and response to influenza -- The NS1 protein: a multitasking virulence factor -- Role of NK cells in influenza infection -- Host detection and the stealthy phenotype in influenza virus infection -- Inactivated and adjuvanted influenza vaccines -- Live attenuated influenza vaccine -- Design of alternative live attenuated influenza virus vaccines -- Rapid production of synthetic influenza vaccines -- Influenza neuraminidase as a vaccine antigen -- Advances in universal influenza virus vaccine design and antibody mediated therapies based on conserved regions of the hemagglutinin -- Structural characterization of epitopes recognized by broadly cross-reactive antibodies -- Skin immunization with influenza vaccines -- Mucosal immunization and adjuvants -- B cell responses to infection and vaccination -- Memory CD4 T cells in influenza -- The effector T cell response to influenza infection -- Antiviral Effects of Inhibiting Host Gene Expression.   .

Sommario/riassunto

This two-volume work covers the molecular and cell biology, genetics and evolution of influenza viruses, the pathogenesis of infection, resultant host innate and adaptive immune response, prevention of infection through vaccination and approaches to the therapeutic control of infection.. Experts at the forefront of these areas provide critical assessments with regard to influenza virology, immunology, cell and molecular biology, and pathogenesis. Volume I provides overviews of the latest findings on molecular determinants of viral pathogenicity, virus entry and cell tropism, pandemic risk assessment, transmission and pathogenesis in animal species, viral evolution, ecology and antigenic variation, while Volume II focuses on the role of innate and adaptive immunity in pathogenesis, development of vaccines and antivirals.  .