Intro -- Preface -- Acknowledgements -- Contents -- Abbreviations -- 1 Understanding Enzymatic Kinetic Resolution -- 1.1 Enzymatic Kinetic Resolution (EKR): Importance -- 1.2 Negativities of Enzymatic Kinetic Resolutions -- 1.3 Enzymatic Kinetic Resolution: Understanding the Process -- 1.4 Kinetic Resolution and Desymmetrization -- References -- 2 Essential Parameters: Determination and Significance -- 2.1 Parameters of EKR -- 2.1.1 Enantiomeric Excess (ee) -- 2.1.2 Determination of ee -- 2.1.3 Enantioselectivity, E: Concepts in Biocatalysis -- 2.2 Enantioselectivity, Enantiomeric Excess and Conversion During the Course of an EKR -- 2.2.1 Dependence of the Substrate ee on Conversion -- 2.2.2 "E is More Significant than ee" -- 2.2.3 Dependence of the Product ee on Conversion -- 2.3 Condition for a High Enantioselectivity -- References -- 3 Enantioselectivity: The Decisive Factors -- 3.1 Factors Affecting Enantioselectivity -- 3.1.1 Effect of Temperature -- 3.1.2 Effect of Water Content -- 3.1.3 Effect of the Presence of Water Miscible Organic Co-solvents -- 3.1.4 Effect of Immobilization -- 3.1.5 Choice of the Acyl Donor: EKR via Transacylation -- 3.2 Uses of Lipases for Kinetic Resolution: Examples -- 3.3 Use of Proteases for EKR -- 3.4 Opposite Enantiopreference by Hydrolases: The Kazlauskas' Model -- References -- 4 Dynamic Kinetic Resolution -- 4.1 DKR: Understanding the Process -- 4.2 DKR of Secondary Alcohols and Amines: Use of Ruthenium -- 4.2.1 Use of Lipase-Ruthenium Combination -- 4.2.2 |