Endocannabinoids / / edited by Loren Parsons, Matthew Hill

• Record Nr.: UNINA9910797822103321
• Pubbl/distr/stampa: Amsterdam : , : Elsevier Science, , 2015
• ISBN: 0-12-801278-1; 0-12-801376-1
• Edizione: [First edition.]
• Descrizione fisica: 1 online resource (368 p.)
• Collana: International review of neurobiology, , 0074-7742 ; ; volume one hundred and twenty-five
• Soggetti: Cannabinoids; Cannabinoids - Receptors; Cannabinoids - Physiological effect
• Lingua di pubblicazione: Inglese
• Formato: Materiale a stampa
• Livello bibliografico: Monografia
• Note generali: Description based upon print version of record.
• Nota di bibliografia: Includes bibliographical references and index.
• Nota di contenuto: Front Cover; Endocannabinoids; Copyright; Contents; Contributors; Preface; Chapter One: The Endocannabinoid Signaling System in the CNS: A Primer; 1. Introduction; 2. The Endocannabinoids; 2.1. Definitions; 2.2. Mechanisms of AEA Biosynthesis; 2.2.1. Precursor Synthesis; 2.2.2. NAPE Conversion to NAE: NAPE-PLD; 2.2.3. NAPE Conversion to NAE: Multienzyme Pathways; 2.2.4. AEA Synthesis from AA; 2.2.5. Summary; 2.3. Mechanisms of AEA Hydrolysis; 2.3.1. Fatty Acid Amide Hydrolase; 2.3.2. NAE-Hydrolyzing Acid Amidase: A Peripheral AEA Hydrolase; 2.4. Mechanisms of 2-AG Biosynthesis; 2.4.1. Diacylglycerol Lipase2.4.2. Mechanisms of DAG Synthesis; 2.5. Mechanisms of 2-AG Catabolism; 2.5.1. Monoacylglycerol Lipase; 2.5.2. Other Enzymes that Hydrolyze 2-AG in the Brain; 2.5.3. Contribution of 2-AG to AA Concentrations; 2.6. Other Inactivation Mechanisms for AEA and 2-AG; 2.6.1. Uptake, Accumulation, and Sequestration; 2.6.2. Oxygenation of the Arachidonate Backbone; 3. Endocannabinoid Receptors; 3.1. Introduction; 3.2. CB1 Cannabinoid Receptors; 3.2.1. CB1R Signaling; 3.2.2. CB1R Pharmacology; 4. CB1R and Retrograde Regulation of Synaptic Activity; 4.1. The Basic Paradigms; 4.1.1. Short-Term Depression of Synaptic Transmission4.1.2. Long-Term Depression of Transmission; 5. Summary; Acknowledgments; ; References; Chapter Two: Evidence for a Role of Adolescent Endocannabinoid Signaling in Regulating HPA Axis Stress Responsivity and E ...; 1. Adolescence and Pubertal Maturation; 2. The Neurobiology of Stress; 3. Adolescent HPA Axis Development; 4. The Developmental Influence of Gonadal Hormones on the HPA Axis; 5. The Endocannabinoid System; 6. Endocannabinoid System Regulation of the HPA Axis in Adulthood; 7. Ontogeny of the Endocannabinoid System; 8. Adolescent HPA Axis Function: A Regulatory Role for the Endocannabinoid System?8.1. Adolescent Stress Exposure Modulates Corticolimbic Endocannabinoid Signaling; 8.2. Adolescent Cannabinoid Exposure Modifies Adult Stress-Induced HPA Axis Activity; 8.3. Long-Term Consequences of Adolescent Endocannabinoid System Dysregulation on the Developing Brain and Behavior; 9. Concluding Remarks; Acknowledgments; References; Chapter Three: The Endocannabinoid System and Its Role in Regulating the Intrinsic Neural Circuitry of the Gastrointestin...; 1. Introduction; 2. The Enteric Nervous System and the Brain-Gut Axis2.1. The Structure of the ENS; 3. The Endocannabinoid System; 3.1. Cannabinoid Receptors and Their Ligands; 3.2. Cannabinoid Receptors in the ENS; 3.3. Endocannabinoid Synthesis; 3.4. 2-AG Synthesis and Degradation; 3.5. Anandamide Synthesis and Degradation; 4. Endocannabinoid Signaling Mechanisms; 4.1. Endocannabinoid Transport Mechanisms; 5. Other Receptors, Agonists, and Antagonists; 5.1. Phytocannabinoids; 5.2. Peptide Endocannabinoids; 5.3. Transient Receptor Potential Vanilloid 1; 5.4. Virodhamine, an Endogenous CB1 Antagonist; 5.5. G Protein-Coupled Receptor 55

The anthropology of sport and human movement [[electronic resource] ] : a biocultural perspective / / edited by Robert R. Sands, Linda R. Sands

• Record Nr.: UNINA9910785671403321
• Pubbl/distr/stampa: Lanham, Md., : Lexington Books, c2010
• ISBN: 1-282-96693-6; 9786612966934; 0-7391-4941-5
• Descrizione fisica: 1 online resource (367 p.)
• Altri autori (Persone): SandsRobert R; SandsLinda R
• Disciplina: 612.7/6
• Soggetti: Sports - Anthropological aspects; Human mechanics
• Lingua di pubblicazione: Inglese
• Formato: Materiale a stampa
• Livello bibliografico: Monografia
• Note generali: Description based upon print version of record.
• Nota di bibliografia: Includes bibliographical references and index.
• Nota di contenuto: Contents; Preface; Acknowledgments; Part 1. FOUNDATIONS; Chapter 1. Anthropology Revisits Sport through Human Movement; Chapter 2. Impact of the Concept of Culture on the Concept of Man; Chapter 3. From Landscapes to Playscapes: The Evolution of Play in Humans and Other Animals; Part 2. EVOLUTION OF HUMAN RUNNING: THE PRECURSOR TO SPORT; Chapter 4. Endurance Predator; Chapter 5. Thermoregulation and Hydrating Strategies in Human Evolution; Chapter 6. Homo cursor: Running into the Pleistocene; Part 3. CULTURE, GENES, RACE, AND PERFORMANCE; Chapter 7. Traditional and Modern Running Culture among the Kalenjin of Kenya: A Historical and Anthropological PerspectiveChapter 8. Black Like Me: The Shared Origins of Humanity and Why We Are Different; Chapter 9. "White" Men Can't Run: Where is the Scientific Evidence?; Part 4. PAST, PRESENT, AND FUTURE; Chapter 10. The Paleolithic Athlete: The Original Cross Trainer; Chapter 11. When Pain = Strain = No Gain: The "Physiology of Strain" and Exercise Intensity, c. 1850-1920; Chapter 12. Throwing like a Brazilian: On Ineptness and a Skill-Shaped Body; Chapter 13. The DREAM Gene for the Posthuman Athlete: Reducing Exercise-Induced Pain Sensations Using Gene TransferIndex; Contributors
• Sommario/riassunto: The Anthropology of Sport and Human Movement represents a collection of work that reveals and explores the often times dramatic relationship of our biology and culture that is inextricably woven into a tapestry of movement patterns. It explores the underpinning of human movement, reflected in play, sport, games and human culture from an evolutionary perspective and contemporary expression of sport and human movement.