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Record Nr. |
UNINA9910797784003321 |
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Autore |
Slesinger Paul A. |
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Titolo |
Structure to function of G protein-gated inwardly rectifying (GIRK) channels / / Paul A. Slesinger, Kevin Wickman |
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Pubbl/distr/stampa |
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Amsterdam, [Netherlands] : , : Academic Press, , 2015 |
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©2015 |
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ISBN |
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0-12-802458-5 |
0-12-802631-6 |
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Edizione |
[First edition.] |
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Descrizione fisica |
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Collana |
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International Review of Neurobiology, , 0074-7742 |
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Disciplina |
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Soggetti |
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G proteins |
Potassium channels |
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Lingua di pubblicazione |
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Formato |
Materiale a stampa |
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Livello bibliografico |
Monografia |
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Note generali |
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Description based upon print version of record. |
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Nota di bibliografia |
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Includes bibliographical references at the end of each chapters and index. |
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Nota di contenuto |
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Unifying mechanism of controlling Kir3 channel activity by G proteins and phosphoinositides -- The roles of G[beta gamma] and G[alpha] in gating and regulation of GIRK channels - RGS redundancy and implications in GPCR-GIRK signaling -- Structural insights into GIRK channel function -- Localization and targeting of GIRK channels in mammalian central neurons -- GIRK channel plasticity and implications for drug addiction --- GIRK channels: a potential link between learning and addiction -- Behavioral and genetic evidence for GIRK channels in the CNS: role in physiology, pathophysiology, and drug addiction. |
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