Characterisation and design of tissue scaffolds / / edited by Paul Tomlins ; contributors, S. F. Badylak [and twenty others]

• Record Nr.: UNINA9910797776903321
• Pubbl/distr/stampa: Amsterdam, [Netherlands] : , : Woodhead Publishing, , 2016; ©2016
• ISBN: 1-78242-087-8; 1-78242-095-9
• Descrizione fisica: 1 online resource (296 p.)
• Collana: Woodhead Publishing Series in Biomaterials ; ; Number 106
• Disciplina: 610.284
• Soggetti: Tissue engineering - Materials; Tissue scaffolds; Biomedical materials
• Lingua di pubblicazione: Inglese
• Formato: Materiale a stampa
• Livello bibliografico: Monografia
• Note generali: Description based upon print version of record.
• Nota di bibliografia: Includes bibliographical references at the end of each chapters and index.
• Nota di contenuto: ""Front Cover""; ""Characterisation and Design of Tissue Scaffolds""; ""Copyright Page""; ""Contents""; ""List of contributors""; ""Woodhead publishing series in biomaterials""; ""1 Material types for tissue scaffolds""; ""Introduction""; ""Polymers""; ""Naturally occurring polymers""; ""Polysaccharides""; ""Alginates""; ""Chitosan""; ""Xanthan""; ""Proteins""; ""Collagen""; ""Fibrin and fibrinogen""; ""Hyaluronic acid""; ""Synthetic polymers""; ""Polyesters""; ""Polyethers""; ""Synthetic proteins""; ""Ceramics""; ""De-cellularized matrices""; ""Characterization of materials""; ""Sterilization""""Future trends""; ""Sources of further information""; ""References""; ""2 Designing and modeling pore size distribution in tissue scaffolds""; ""Background""; ""Modeling of pore architecture and its effect on the process of tissue engineering""; ""Selection of fabrication technique in terms of pore size distribution-with emphasis on polymer-based scaffolds""; ""Electrospinning of tissue engineered vascular grafts-the effect of pore morphology on the mechanical and biological functio...""; ""Conclusion""; ""References""; ""3 Computer modeling of the degradation behavior of polyester-based tissue engineering scaffolds""""Introduction""; ""Tissue engineering ; scaffolds""; ""Factors controlling the degradation rate of scaffolds""; ""Material factors""; ""The effect of geometry""; ""Environmental conditions""; ""A mathematical model for the degradation of bioresorbable polyesters""; ""Degradation maps""; ""Computer modeling of scaffold degradation using finite element methods""; ""FE modeling procedure""; ""Foamlike scaffolds""; ""Size effect zone""; ""Molecular weight""; ""Scission rate""; ""Short chain diffusion""""Fibrous scaffolds""; ""Size effect zone""; ""Molecular weight""; ""Scission rate""; ""Short chain diffusion""; ""Conclusion""; ""References""; ""4 Decellularization of mammalian tissues: preparing extracellular matrix bioscaffolds""; ""Introduction""; ""Rationale and relevance for clinical use of decellularized tissues""; ""Establishing a criteria for decellularization efficacy""; ""Decellularization agents""; ""Hypertonic and hypotonic solutions""; ""Acids and alkaline bases""; ""Acids""; ""Alkaline bases""; ""Detergents""; ""Nonionic detergents""; ""Ionic detergents""""Zwitterionic detergents""; ""Solvents""; ""Tri(n-butyl)phosphate""; ""Alcohols""; ""Biological agents""; ""Enzymes""; ""Nonenzymatic biologic agents""; ""Chelating agents""; ""Toxins""; ""Decellularization techniques""; ""Immersion and agitation""; ""Use of pressure as a decellularization technique""; ""Supercritical fluid""; ""Perfusion decellularization of whole organ constructs""; ""Terminal sterilization of decellularized tissues""; ""Decellularization agents that act as disinfectants""; ""Depyrogenation""; ""Ionizing radiation""; ""Ethylene oxide exposure""; ""Conclusion""