1.

Record Nr.

UNINA9910797030603321

Titolo

Textbook of receptor pharmacology / / edited by John C. Foreman, Torben Johansen and Alasdair J. Gibb

Pubbl/distr/stampa

Boca Raton, FL : , : CRC Press, an imprint of Taylor and Francis, , 2010

ISBN

0-429-14730-9

1-4200-5255-1

Edizione

[Third edition.]

Descrizione fisica

1 online resource (314 p.)

Disciplina

615.7

Soggetti

Drug receptors

Lingua di pubblicazione

Inglese

Formato

Materiale a stampa

Livello bibliografico

Monografia

Note generali

Includes index.

Nota di contenuto

Front cover; Contents; Preface; Editors; Contributors; Section I: Drug-Receptor Interactions; Chapter 1. Classical Approaches to the Study of Drug- Receptor Interactions; Section II: Molecular Structure of Receptors; Chapter 2. Structure and Function of 7-TM G-Protein Coupled Receptors; Chapter 3. The Structure of Ligand-Gated Ion Channels; Chapter 4. Molecular Structure of Receptor Tyrosine Kinases; Section III: Ligand-Binding Studies of Receptors; Chapter 5. Direct Measurement of Drug Binding to Receptors; Section IV: Transduction of the Receptor Signal

Chapter 6. Receptors Linked to Ion Channels: Mechanisms of Activation and BlockChapter 7. G-Proteins; Chapter 8. Signal Transduction through Protein Tyrosine Kinases; Section V: Receptors as Pharmaceutical Targets; Chapter 9. Receptors as Pharmaceutical Targets; Index; Back cover

Sommario/riassunto

For the past four decades, University College London has offered a renowned course on receptor pharmacology. Originating from this course, the perennially bestselling Textbook of Receptor Pharmacology has presented in-depth coverage of this rapidly expanding area of research. This third edition continues to combine current understanding of classical quantitative pharmacology and drug-receptor interactions with the basics of receptor structure and signal transduction mechanisms, providing an integrated analysis of the mechanisms of drug action at membrane receptors.