1.

Record Nr.

UNINA9910795977303321

Autore

Bisognano Maureen A

Titolo

Pursuing the triple aim [[electronic resource] ] : seven innovators show the way to better care, better health, and lower costs / / Maureen Bisognano, Charles Kenney

Pubbl/distr/stampa

San Francisco, : Jossey-Bass, c2012

ISBN

1-280-67526-8

9786613652195

1-118-24084-7

1-118-22856-1

Edizione

[1st ed.]

Descrizione fisica

xvii, 327 p

Altri autori (Persone)

KenneyCharles

Disciplina

362.168/1

Soggetti

Medical care - United States - Cost control

Medical care - United States - Quality control

Lingua di pubblicazione

Inglese

Formato

Materiale a stampa

Livello bibliografico

Monografia

Nota di bibliografia

Includes bibliographical references and index.



2.

Record Nr.

UNINA9910678254403321

Titolo

Metabolomics and Its Impact on Health and Diseases / / edited by Veronica Ghini, Kathleen A. Stringer, Claudio Luchinat

Pubbl/distr/stampa

Cham : , : Springer International Publishing : , : Imprint : Springer, , 2023

ISBN

3-031-26859-8

Edizione

[1st ed. 2023.]

Descrizione fisica

1 online resource (384 pages)

Collana

Handbook of Experimental Pharmacology, , 1865-0325 ; ; 277

Disciplina

780

Soggetti

Pharmacology

Biochemical markers

Cytology

Analytical biochemistry

Biomarkers

Cell Biology

Analytical Biochemistry

Lingua di pubblicazione

Inglese

Formato

Materiale a stampa

Livello bibliografico

Monografia

Nota di bibliografia

Includes bibliographical references.

Nota di contenuto

Preface -- Practical Aspects of NMR-Based Metabolomics -- Compound Identification in Mass Spectrometry-Based Metabolomics -- METABOLOMICS USING NMR – Avoiding the ‘Black-Box’ -- Natural products drug discovery: on silica or in silico?- Quantitative NMR Methods in Metabolomics -- Advancements in pulsed stable isotope resolved metabolomics -- Metabolomics in Cell Biology -- NMR-based metabolomics to evaluate individual response to treatments -- Pharmacometabolomics of Asthma as a road map to Precision Medicine -- Prospective metabolomic studies in precision medicine -- Chemotherapy-induced Peripheral Neuropathy -- Metabolomics of Respiratory Diseases.

Sommario/riassunto

This volume of the Handbook of Experimental Pharmacology, which celebrated its 100th anniversary in 2019, addresses the rapidly growing and evolving field of metabolomics. It has been compiled and designed to broaden and enrich your understanding as well as simplify a complicated picture of the diverse field of metabolomics. This is



accomplished by chapters from experts in the field on basic principles as well as reviews and updates of analytical techniques. The variety and different perspectives of the NMR approaches are described in the chapters By David Wishart, Daniel Raftery and Ryan McKay, while mass spectrometry advances are covered by Charles R. Evans and Stefan Kempa. This book also reflects the state of the art in the application of metabolomics to cell biology (Marta Cascante and Ulrich Guenther) and chapters that share insights into the application of metabolomics in various diseases (Paola Turano and Claudio Luchinat, Rachel S. Kelly and JessicaLasky-Su, Paige Lacy, and Angela Rogers. Relationships of metabolomics with drugs are highlighted by Robert Verpoorte (natural products drug discovery), by Oscar Millet and by Turano and Luchinat (perspectives in precision medicine) and by Daniel L. Hertz (drug-induced peripheral neuropathy). From the above list of diverse topics, we believe this book has interdisciplinary appeal and scholars with an interest in the role of metabolomics in achieving precision medicine will find it of particular or special interest.