Microbial evolution and co-adaptation [[electronic resource] ] : a tribute to the life and scientific legacies of Joshua Lederberg : workshop summary / / rapporteurs, David A. Relman ... [et al.]

• Record Nr.: UNINA9910792343303321
• Pubbl/distr/stampa: Washington, D.C., : National Academies Press, 2009
• ISBN: 0-309-17731-6; 0-309-13122-7
• Descrizione fisica: 1 online resource (329 p.)
• Altri autori (Persone): LederbergJoshua; RelmanDavid A
• Disciplina: 579/.135
• Soggetti: Microorganisms - Evolution; Communicable diseases; Evolution; Adaptation (Biology)
• Lingua di pubblicazione: Inglese
• Formato: Materiale a stampa
• Livello bibliografico: Monografia
• Note generali: Bibliographic Level Mode of Issuance: Monograph
• Nota di bibliografia: Includes bibliographical references.
• Nota di contenuto: Workshop overview -- Appendix: WO-1. Infectious history / Joshua Lederberg -- The life and legacies of Joshua Lederberg -- Reflections on the career of Joshua Lederberg / David A. Hamburg -- Joshua Lederberg remembered / Stephen S. Morse -- The life and impact of a legend-Joshua Lederberg / Adel Mahmoud -- Microbial ecology and ecosystems -- War and peace: humans and their microbiome / David A. Relman -- Deciphering the complex molecular dialogue of symbiosis: Esperanto or polyglot? / Margret McFall-Ngai -- Pathogen evolution -- Bacterial pathogenicity: an historical and experimental perspective / Stanley Falkow -- Evolution of bacterial-host interactions: virulence and the immune overresponse / Elisa Margolis and Bruce R. Levin -- Antibiotic resistance: origins and countermeasures -- Antibiotic resistance and the future of antibiotics / Julian Davies -- Microbial drug resistance: an old problem in need of new solutions / Stanley N. Cohen -- Expanding the microbial universe: metagenomics and microbial community dynamics / Jo Handelsman -- Infectious disease emergence: past, present, and future -- Emerging infections: ; condemned to repeat? / Stephen S. Morse -- Ecological origins of novel human pathogens / Mark Woolhouse and Eleanor Gaunt -- Genomic evolvability and the origin of novelty: studying the past, interpreting the present, and predicating the future / Jonathan A. Eisen -- Can we predict future trends in disease emergence? / Peter Daszak -- Appendices: A. Agenda -- B. Acronyms -- C. Glossary -- D. Forum member biographies.
• Sommario/riassunto: "Dr. Joshua Lederberg - scientist, Nobel laureate, visionary thinker, and friend of the Forum on Microbial Threats - died on February 2, 2008. It was in his honor that the Institute of Medicine's Forum on Microbial Threats convened a public workshop on May 20-21, 2008, to examine Dr. Lederberg's scientific and policy contributions to the marketplace of ideas in the life sciences, medicine, and public policy. The resulting workshop summary, Microbial Evolution and Co-Adaptation, demonstrates the extent to which conceptual and technological developments have, within a few short years, advanced our collective understanding of the microbiome, microbial genetics, microbial communities, and microbe-host-environment interactions."