1.

Record Nr.

UNINA9910789920103321

Titolo

The handbook of operator fatigue / / edited by Gerald Matthews, P.A. Hancock, Paula A. Desmond

Pubbl/distr/stampa

[Place of publication not identified] : , : CRC Press, , 2017

ISBN

1-315-55736-3

1-317-02941-0

1-317-02940-2

1-280-68992-7

9786613666864

1-4094-4265-9

Edizione

[First edition.]

Descrizione fisica

1 online resource (531 p.)

Disciplina

612.744

Soggetti

Fatigue

Fatigue - Physiological aspects

Fatigue - Diagnosis

Fatigue - Prevention

Motor vehicle drivers - Safety measures

Local transit - Employees - Health and hygiene

Lingua di pubblicazione

Inglese

Formato

Materiale a stampa

Livello bibliografico

Monografia

Note generali

Description based upon print version of record.

Nota di bibliografia

Includes bibliographical references and index.

Nota di contenuto

Cover; Contents; List of Figures; List of Tables; The Editors; The Contributors; Part I  Introduction to Operator Fatigue; 1 An Overview of Operator Fatigue; 2 An Historical View of Operator Fatigue; 3 Challenges in Fatigue and Performance Research; Part II The Nature of Fatigue; 4 Conceptualizing and Defining Fatigue; 5 Individual Differences in Stress, Fatigue and Performance; 6 Task Characteristics and Fatigue; 7 Fatigue in Sports Psychology; Part III Assessment of Fatigue; 8 Approaches to the Measurement of Fatigue; 9 Dimensional Models of Fatigue

10 Models of Individual Differences in Fatigue for Performance ResearchPart IV The Neuroscience of Fatigue; 11 Neuroscience of Sleep and Circadian Rhythms; 12 The Influence of Fatigue on Brain Activity;



13 Cerebral Hemodynamic Indices of Operator Fatigue in Vigilance; 14 Biochemical Indices of Fatigue for Anti-fatigue Strategies and Products; Part V Performance Effects of Sleep Loss  and Circadian Rhythms; 15 Socio-emotional and Neurocognitive Effects of Sleep Loss; 16 Circadian Rhythms and Mental Performance; 17 Sleep Loss and Performance; Part VI Fatigue and Health

18 Differentiating Fatigue in Chronic Fatigue Syndrome and Psychiatric Disorders19 Chronic Fatigue Syndrome; 20 Upper Respiratory Tract Illnesses and Fatigue; Part VII Applied Contexts for Operator Fatigue; 21 Long Work Hours, Fatigue, Safety, and Health; 22 Fatigue and Road Safety; 23 Driver Fatigue and Safety: A Transactional Perspective; 24 Understanding and Managing Fatigue in Aviation; 25 Soldier Fatigue and Performance Effectiveness: Yesterday, Today and Tomorrow; Part VIII Operational Countermeasures; 26 Adaptive Automation for Mitigation of Hazardous States of Awareness

27 Countermeasures for Driver Fatigue28 Work Scheduling; 29 Avoiding the Impact of Fatigue on Human Effectiveness; 30 Model-based Fatigue Risk Management; Index

Sommario/riassunto

"Fatigue is a recognized problem in many facets of the human enterprise. It is not confined to any one area of activity but enters all situations in which humans have to perform for extended intervals of time. Most problematic are the circumstances in which obligatory action is continuous and the results of failure are evidently serious or even catastrophic. Therefore, the modern media especially highlights fatigue-related failures in industries such as transportation, materials processing and healthcare. It can be, and indeed is, no coincidence that most of the spectacular failures in process control that have resulted in the world's largest industrial accidents have occurred in the small hours of the morning when the circadian rhythm is lowest and operator fatigue itself peaks. While there have been legislative efforts made at state, federal and international levels to regulate working hours of employees, the appropriate implementation of such legislation is still a long way off. The Handbook of Operator Fatigue provides a comprehensive account of the subject to serve as the definitive reference work for researchers, students and practitioners alike. The volume features 30 chapters written by experts from around the world to address each important facet of fatigue, including: the scale of the fatigue problem (Section I), the nature of fatigue (Section II), how to assess fatigue (Section III), the impact of fatigue on health (Section IV), fatigue in the workplace (Section V), the neurological basis of fatigue (VI), sleep disorders (VII), and the design of countermeasures to fatigue (VIII)."--Provided by publisher.



2.

Record Nr.

UNINA9910367754503321

Autore

Mallis Panagiotis

Titolo

Stem Cell and Biologic Scaffold Engineering / Panagiotis Mallis

Pubbl/distr/stampa

MDPI - Multidisciplinary Digital Publishing Institute, 2019

Basel, Switzerland : , : MDPI, , 2019

ISBN

9783039214983

3039214985

Descrizione fisica

1 electronic resource (110 p.)

Soggetti

Biology, life sciences

Lingua di pubblicazione

Inglese

Formato

Materiale a stampa

Livello bibliografico

Monografia

Sommario/riassunto

Tissue engineering and regenerative medicine is a rapidly evolving research field which effectively combines stem cells and biologic scaffolds in order to replace damaged tissues. Biologic scaffolds can be produced through the removal of resident cellular populations using several tissue engineering approaches, such as the decellularization method. Indeed, the decellularization method aims to develop a cell-free biologic scaffold while keeping the extracellular matrix (ECM) intact. Furthermore, biologic scaffolds have been investigated for their in vitro potential for whole organ development. Currently, clinical products composed of decellularized matrices, such as pericardium, urinary bladder, small intestine, heart valves, nerve conduits, trachea, and vessels, are being evaluated for use in human clinical trials. Tissue engineering strategies require the interaction of biologic scaffolds with cellular populations. Among them, stem cells are characterized by unlimited cell division, self-renewal, and differentiation potential, distinguishing themselves as a frontline source for the repopulation of decellularized matrices and scaffolds. Under this scheme, stem cells can be isolated from patients, expanded under good manufacturing practices (GMPs), used for the repopulation of biologic scaffolds and, finally, returned to the patient. The interaction between scaffolds and stem cells is thought to be crucial for their infiltration, adhesion, and



differentiation into specific cell types. In addition, biomedical devices such as bioreactors contribute to the uniform repopulation of scaffolds. Until now, remarkable efforts have been made by the scientific society in order to establish the proper repopulation conditions of decellularized matrices and scaffolds. However, parameters such as stem cell number, in vitro cultivation conditions, and specific growth media composition need further evaluation. The ultimate goal is the development of "artificial" tissues similar to native ones, which is achieved by properly combining stem cells and biologic scaffolds and thus bringing them one step closer to personalized medicine. The original research articles and comprehensive reviews in this Special Issue deal with the use of stem cells and biologic scaffolds that utilize state-of-the-art tissue engineering and regenerative medicine approaches.